http://www.newscientistjobs.com/jobsNew Scientist Jobshttp://www.newscientistjobs.com/jobs/job/formulation-scientist-225337-nj-new-jersey-200645875.htmFri, 20 Nov 2009 20:59:35 +0000196366A leader in therapeutic antibodies, ImClone Systems is committed to advancing oncology care by developing a portfolio of novel targeted biologic treatments designed to address the medical needs of patients with a variety of cancers. Founded 25 years ago, ImClone Systems has a rich culture of biotechnology innovation and leading-edge medical science. Our deep expertise in molecular biology, oncology, genomics and antibody engineering has helped us establish a robust pipeline of products that are in various stages of clinical development and span virtually all major solid tumor types. ESSENTIAL DUTIES AND RESPONSIBILITIES 1. Assists in the development of formulations for protein therapeutics. 2. Operation of analytical instrumentation including: HPLC, Electrophoresis (SDS-PAGE and IEF), Spectrophotometer, CD, Fluorimeter, DSC, FTIR, HIAC, DLS, pH meter, Conductivity Meter, Osmometer and Freeze Dryer. 3. Execute experiments, analyze data, and report results to supervisor within timelines. 4. Active participation with supervisor in planning and executing experiments. 5. Write SOP’s, study protocols and technical reports. 6. Sample management and monitoring of stability samples. 7. Assay development and trouble shooting. 8. Assist in the development of final drug dosage forms. 9. Maintain Laboratory and Laboratory Records. 10. Work in a safe manor compliant to ImClone Systems policies and procedures. ESSENTIAL KNOWLEDGE, SKILLS, EXPERIENCE 1. BS in Biochemistry/Pharmaceutical Science with 8-12 years of relevant industry experience or MS in Biochemistry/Pharmaceutical Science with 4-8 years of relevant industry experience. 2. Knowledge of the use of and experience with Spectrophotometer, CD, Fluorimeter, DSC and HPLC is preferable. 3. Must have good written and oral communication skills. 4. Must have good organization and documentation skills. 5. Must have the ability to accurately prepare solutions, perform experiments and analyze data. 6. Must be detail orientated and have demonstrated time management skills. To apply please visit http://www.imclone.com/careers_imclone.php,Requisition #225337. http://www.newscientistjobs.com/jobs/job/formulation-associate-nj-new-jersey-200628453.htmTue, 10 Nov 2009 14:39:25 +0000175999A leader in therapeutic antibodies, ImClone Systems is committed to advancing oncology care by developing a portfolio of novel targeted biologic treatments designed to address the medical needs of patients with a variety of cancers. Founded 25 years ago, ImClone Systems has a rich culture of biotechnology innovation and leading-edge medical science. Our deep expertise in molecular biology, oncology, genomics and antibody engineering has helped us establish a robust pipeline of products that are in various stages of clinical development and span virtually all major solid tumor types. The Formulation Associate will be responsible for assisting in the development of formulations for protein therapeutics, to include buffer preparation, stability studies and investigations for compatibility and delivery problems. ESSENTIAL DUTIES AND RESPONSIBILITIES 1. Operation of Spectrophotometer, pH meter, Conductivity Meter and Electrophoresis Apparatus (i.e. SDS-PAGE, IEF) 2. Operation of analytical HPLC (SEC, IEC and RP) 3. Assists in the development of analytical methods for protein analysis 4. Buffer preparation 5. Perform routine assays to test the chemical stability of proteins in relation to excipients and storage conditions 6. Data entry 7. Assay development and trouble shooting 8. Assist in the development of final drug dosage forms 9. Maintain Laboratory and Laboratory Records 10. Work in a safe manner and be compliant to ImClone Systems policies and procedures ESSENTIAL KNOWLEDGE, SKILLS, EXPERIENCE 1. BS with 2-6 years of experience, MS with 1-4 years of experience 2. Knowledge of the use of and experience with spectrophotometry, electrophoresis (SDS-PAGE and IEF), HPLC. 3. Knowledge of protein chemistry with experience in protein sample analysis and handling. 4. Knowledge and experience in buffer preparation. 5. Knowledge of and operation of biophysical analytical instrumentation will be a plus (Fluorimeter, DSC, HIAC, DLS and Osmometer). http://www.newscientistjobs.com/jobs/job/national-exposure-research-laboratory-post-doctoral-research-program-united-states-200629355.htmTue, 03 Nov 2009 23:03:06 +0000165199• The National Exposure Research Laboratory (NERL) of the United States Environmental Protection Agency is accepting applications beginning November 2, 2009 through January 11, 2010 for approximately 10 federal, three-year post-doctoral research positions. • Candidates will engage in research in areas such as: computer modeling of the transport, transformation, and fate of pollutants in multiple media and at multiple scales, hydrologic modeling, GIS mapping and interpretation for human exposure, demographics related to ecological exposure, modeling of microbial fate and exposure, and exposure modeling for epidemiological studies. • Specific research opportunities are posted on the NERL website at http://www.epa.gov/nerl • Post-doctoral positions will be in one or more of the following locations: Research Triangle Park, North Carolina; Cincinnati, Ohio; Las Vegas, Nevada; or Athens, Georgia. FULL FEDERAL EMPLOYMENT BENEFITS • Salary range of $67,613 - $91,305 (subject to increase in January 2010) • Full three-year appointments • Paid relocation to EPA duty location • Vacation and sick leave • Federal health benefits, life insurance, and retirement program • Travel to professional and scientific meetings • Flexible start date beginning in March/April and no later than September 2010 APPLICATION PROCESS – Consult the NERL website at http://www.epa.gov/nerl for instructions on how to apply. Note – online applications from journal websites are not accepted. Applicants must provide: • Up-to-date Curriculum Vitae • Letter of recommendation from your research advisor or comparable official • Cover letter indicating: o positions and locations of interest o your email address o U.S. Citizenship status, AND o How you learned of this program (If you first learned of the program at an online website, please provide name of website.) • DD-214, if claiming veteran’s preference • Applicants must be United States citizens or permanent residents. Only in the absence of qualified U.S. citizens will permanent residents who are citizens of countries specified as exceptions to the appropriations act ban on paying non-U.S. citizens be considered. Specific job information is posted on the NERL Internet site at http://www.epa.gov/nerl. EPA provides reasonable accommodations to applicants with disabilities. If you need a reasonable accommodation for any part of the application and hiring process, please notify the Agency. The decision on granting reasonable accommodation will be on a case by case basis. The U.S. EPA is an Equal Opportunity Employer http://www.newscientistjobs.com/jobs/job/director-process-dev-mgmt-ca-california-200627247.htmMon, 02 Nov 2009 04:27:09 +0000162089Responsibilities: The Protein Analytical Chemistry Department in Genentech's Quality Bioanalytical Development organization has a Director-level opportunity for an accomplished analytical scientist to lead a talented and dedicated department. She/he will need to be able to develop strategies and influence internal and external practices regarding analytical characterization, method development and validation, and method transfers to testing groups. This leader will also play a key role in regulatory negotiations. The successful candidate will need to establish and maintain important internal collaborations with other functions, including research, bioprocessing, quality, regulatory, and pharmaceutical development. She/he will also need to be able to identify emerging analytical technologies, and be able to oversee the department's efforts to convert new technologies into mainstream approaches in PAC and associated departments. Requirements: The successful candidate will have a Ph.D. in chemistry, biochemistry, or a related area with 10+ years of analytical protein chemistry experience and 5+ years leading scientist-level staff and/or cross-functional teams. This person will also have a track record of accomplishment in translating innovative science into successful analytical strategies, and relevant experience managing a business unit. This position requires demonstrated evidence of the candidate's ability to hire, develop and manage a staff of approximately 30 RAs and Scientists  Experience with conjugated proteins and contract laboratories will be a plus. This leader must understand process development strategies and clinical GMP requirements.   DIVISION:  Process Dev & New Manuf Facil REQUISITION NUMBER:  09-1000028872 http://www.newscientistjobs.com/jobs/job/assoc-director-quality-ca-california-200627236.htmMon, 02 Nov 2009 04:24:50 +0000162080Associate Director, Quality Bioanalytical Development Method Validation There is an Associate Director position available in Protein Analytical Chemistry, a part of Genentech's Quality Bioanalytical Development organization, to an accomplished individual with experience in method validation for commercial filings.  The responsibilities of this individual will include leading a group to oversee method validation for licensure of new products, developing efficient approaches to phase appropriate method qualification and validation, and ensuring compliance with GLP/GMP requirements and Genentech Quality Systems. The successful candidate will have a Ph.D. (or equivalent) in chemistry, biochemistry, or a related area with 10+ years experience in a protein therapeutics Quality Control environment.  She/he must have demonstrated a solid understanding of GMP requirements for method validation and testing for US and European regulatory filings to support clinical development and licensure.  S/he must have the ability to develop, execute and defend phase-appropriate validation strategies.  Strong managerial skills are required, including hiring and developing staff.   The successful candidate is expected to exhibit strong teamwork and collaborative skills with outstanding verbal and written communication. DIVISION:  Process Dev & New Manuf Facil REQUISITION NUMBER:  09-1000028363 http://www.newscientistjobs.com/jobs/job/postdoctoral-associate-microfluidics-specialist-va-virginia-200611265.htmFri, 16 Oct 2009 13:40:19 +0000141647The Virginia Bioinformatics Institute (VBI) is a research institute dedicated to the study of the biological sciences. By using bioinformatics, which combines transdisciplinary approaches to information technology and biology, researchers at VBI interpret and apply vast amounts of biological data generated from basic research to some of today's key challenges in the biomedical sciences. VBI develops genomic, proteomic and bioinformatics tools that can be applied to the study of infectious diseases as well as the discovery of new vaccines, drugs and diagnostic targets. VBI strongly emphasizes synergistic interactions among faculty and is organized around the concept of team science. The Microfluidics group at VBI, aimed at developing fully integrated, stand-alone microfluidic devices with mass spectrometry detection for high-throughput proteomic investigations, currently seeks a Postdoctoral Associate for Microfluidics and Mass Spectrometry research. The Postdoctoral Associate will work as part of a team of scientists and researchers who design and evaluate the performance of microfluidic devices. The Postdoctoral Associate will be responsible for developing multidimensional separations with mass spectrometry detection on the chip, and for performing microfluidic flow modeling. The chips will be used for the analysis of cellular extracts and biomarker discovery/screening applications. Required Qualifications: -Ph.D. in Chemistry or Engineering or related field. -Demonstrated experience with microfluidic chip operation. -Experience using commercial software for modeling microfluidic flows. -Ability to work independently as well as with research group. -Good communication skills, strong work habits and motivation. Preferred Qualifications: -Experience with bioanalytical instrumentation. Interested candidates should submit a letter of interest and CV upon by clicking Apply Now below and searching by posting number 090377. Review of applications will begin for this position on July 22, 2009. Compensation commensurate with experience. To learn more about VBI, please visit our website. An Equal Opportunity/Affirmative Action Institute http://www.newscientistjobs.com/jobs/job/nasa-postdoctoral-fellowships-al-alabama-200402589.htmTue, 07 Apr 2009 14:43:10 +00008785NASA Postdoctoral Fellowships The NASA Postdoctoral Program (NPP) offers unique research opportunities to highly talented national and international scientists to engage in ongoing NASA research in space science, earth science, aeronautics, space operations, exploration systems, and astrobiology. Awards: • Approximately 50 Fellowships awarded annually • One-year appointments, renewable up to three years • Annual stipends start at $50,000, with supplements for specific degree fields and high cost-of-living areas • Annual travel budget of $8,000 • Financial assistance for relocation • Financial supplement for health insurance purchased through the program • Apply at http://nasa.orau.org/postdoc Application Deadlines: Three each year - March 1, July 1, and November 1 Eligibility: • U.S. Citizen • Foreign Nationals with a J-1 visa status as a research scholar, Lawful Permanent Resident (LPR) status, or Employment Authorization Document (EAD with pending LPR status • Recent and senior-level Ph.D. recipients Locations of Fellowship Positions: • Ames Research Center, Moffett Field, CA • Dryden Flight research Center, Edwards, CA • Glenn Research Center, Cleveland, OH • Goddard Space Flight Center, Greenbelt, MD • Jet Propulsion Laboratory, Pasadena, CA • Johnson Space Center, Houston, TX • Kennedy Space Center, Kennedy Space Center, FL • Langley Research Center, Hampton, VA • Marshall Space Flight Center, Huntsville, AL • Stennis Space Center, Stennis Space Center, MS • NASA Headquarters, Washington, DC • Various locations associated with the NASA Astrobiology Institute To obtain more information and to apply for this exciting opportunity, please visit the NPP Web site at http://nasa.orau.org/postdoc