http://www.newscientistjobs.com/jobsNew Scientist Jobshttp://www.newscientistjobs.com/jobs/job/technical-delivery-manager-md-maryland-200642313.htmFri, 20 Nov 2009 22:00:00 +0000197446My company shares my passion for helping to improve human health around the world. This is My MedImmune. Those who join MedImmune feel a sense of ownership about their future. They thrive with a recognized leader in the biotechnology industry and the wholly-owned subsidiary of AstraZeneca plc. Here, you will join passionate professionals who advance science, technology and medicine to develop products designed to help people live better lives. You will excel in an environment characterized by respect, integrity and growth opportunities that encourages both individual contribution and collaborative entrepreneurial thinking. Our products and/or product candidates are designed to address areas of need in infection, oncology, respiratory disease and inflammation, cardiovascular/gastrointestinal disease and neuroscience. Explore a MedImmune career as we strive to better more lives, more often, around the world. Title: Technical Delivery Manager Location: MD, Gaithersburg - Corporate Headquarters Req: 02109 Job Description Position will work in IT addressing the business technology needs within the area of Medical and Regulatory Affairs. Position will be responsible for understanding business problems and working with relationship managers, business analysts and technical teams to develop technology solutions in support of business needs. In addition, position will be responsible for overseeing technology solutions; implementing system-based solutions; and managing vendor partners and internal resources in the delivery and support of technology to satisfy MedImmune's business capability needs. Position will be responsible for technical oversight and management of projects. Position will own technical requirements definition based on functional requirements and taking the solution blueprint, in conjunction with the user requirements, and turning it into a detailed design or configuration. Position will assess the scope of new project efforts by estimating the work involved, resources required and time line for technical delivery efforts. Position owns solution prototyping and change management, blueprinting (fit/gap) and quality assurance; manages the development and delivery activities within SDD in support of project and non-project activities. Has direct responsibility for the overall success of the assigned project and deliverables, either through direct participation or oversight. Projects may include new applications and modules, major or minor enhancements to existing applications or modules and product upgrades. Position will work with business owners, relationship managers and IT to manage the development to production and the production to operations activities following established methodology. Activities include internal code reviews, testing, supporting user acceptance testing, developing a support approach, application training, disaster recovery plans, application process maps and others as defined by the IT PMO. Position will keep customers (to include business owners, relationship managers, and internal IT management) apprised of progress, issues, and risks in a timely manner. Position will practice risk management strategies to ensure that project commitments are realistic and met. Position will participate in the establishment and implementation of SDLC methodologies, ITIL processes and IT PMO processes and ensure that IT projects adhere to those standards and meet customer expectations International travel may be required. Additional requirements for Medical and Regulatory Affairs include: Experience with Medical and Regulatory Affairs in a pharmaceutical or biotech environment. Clinical trials knowledge. Experience with data warehousing and data mining. Skills: Demonstrated ability to manage software development teams, implementation of off the shelf software packages, and interdependencies within an IT development organization. Demonstrated ability to manage cost, schedule, and performance of IT development projects and departments. Demonstrated ability to manage different development resources to include, internal, external, contracted staff augmentation resources, and outsourcing partners. Ability to collaborate and engage IT stakeholders including IT security, Validation/QA, IT Infrastructure, and Enterprise Architecture as needed. Proven ability to identify, manage and mitigate issues and risks. Demonstrated oral and written communication skills. Experience presenting project information in a formal and informal setting. Demonstrated focus on meeting customer expectations and working with a customer service mindset. Demonstrated interpersonal skills with experience managing diverse teams. Demonstrated ability to staff and develop individuals and teams. Demonstrated commitment to staff development and retention. Demonstrated ability to conduct facilitated sessions with end users and business owners in order to define requirements and review project progress. Demonstrated skills in problem identification, isolation and resolution through the use of analysis, troubleshooting and other like techniques. Experience coaching staff on problem resolution techniques Functional Knowledge is necessary in the following areas: Biotech or Pharmaceuticals; Validated Systems Environments; Sarbanes-Oxley Requirements; Data and Application Security; Business Intelligence Processes and Methodology knowledge is necessary in the following areas: Familiarity with ITIL; SDLC processes to include rapid and waterfall development; Project management of multiple development projects; Data Analysis. Experience with electronic publishing processes (e.g. eCTD and other formats), document management (Documentum, LiveLink, etc) is highly desirable. Technical Skills are necessary in the following areas: Application Platforms (SharePoint, SharePoint Portal Server, SharePoint Server 2007, Web Logic, IIS). Application Development (XML, WebServices, Middleware such as BizTalk or BEA Aqua Logic); MS Office Suite of Products; Database and Business Intelligence (Data warehousing, Oracle, TOAD or other similar, SQL Server, MS Access); Development Applications (Visual Studios Team Services, Development management tool such as Rational or visual studio, etc.); Programming Languages (SQL, PL/SQL, Transact-SQL, C#) JOB REQUIREMENTS: Job Requirements Education: Bachelor's degree from accredited college or university is required. Bachelor's or master's degree in computer-related curriculum is desired. Experience: 6+ years of work experience; 4-5+ years of IT work experience, with progressively more responsibility; Proven track record of managing and coordinating several projects simultaneously while delivering on time, on schedule, and meeting customer expectations; Experience project planning from project inception through transition to operational support; 1-2 years in a pharmaceutical, biotech, or consumer goods environment; 2-3 years of managing technical resources to include internal and vendor partners; Ability to provide leadership, management and technical expertise to a culturally diverse, technically-oriented staff If you are interested in this position please click the Apply Now button below and search for Req #. 02109. MedImmune is an Equal Opportunity Employer and does not discriminate on the basis of race, color, religion, gender, age, national origin, disability, veteran status, or any other characteristic protected by federal, state or local law. http://www.newscientistjobs.com/jobs/job/formulation-scientist-225337-nj-new-jersey-200645875.htmFri, 20 Nov 2009 20:59:35 +0000197439A leader in therapeutic antibodies, ImClone Systems is committed to advancing oncology care by developing a portfolio of novel targeted biologic treatments designed to address the medical needs of patients with a variety of cancers. Founded 25 years ago, ImClone Systems has a rich culture of biotechnology innovation and leading-edge medical science. Our deep expertise in molecular biology, oncology, genomics and antibody engineering has helped us establish a robust pipeline of products that are in various stages of clinical development and span virtually all major solid tumor types. ESSENTIAL DUTIES AND RESPONSIBILITIES 1. Assists in the development of formulations for protein therapeutics. 2. Operation of analytical instrumentation including: HPLC, Electrophoresis (SDS-PAGE and IEF), Spectrophotometer, CD, Fluorimeter, DSC, FTIR, HIAC, DLS, pH meter, Conductivity Meter, Osmometer and Freeze Dryer. 3. Execute experiments, analyze data, and report results to supervisor within timelines. 4. Active participation with supervisor in planning and executing experiments. 5. Write SOP’s, study protocols and technical reports. 6. Sample management and monitoring of stability samples. 7. Assay development and trouble shooting. 8. Assist in the development of final drug dosage forms. 9. Maintain Laboratory and Laboratory Records. 10. Work in a safe manor compliant to ImClone Systems policies and procedures. ESSENTIAL KNOWLEDGE, SKILLS, EXPERIENCE 1. BS in Biochemistry/Pharmaceutical Science with 8-12 years of relevant industry experience or MS in Biochemistry/Pharmaceutical Science with 4-8 years of relevant industry experience. 2. Knowledge of the use of and experience with Spectrophotometer, CD, Fluorimeter, DSC and HPLC is preferable. 3. Must have good written and oral communication skills. 4. Must have good organization and documentation skills. 5. Must have the ability to accurately prepare solutions, perform experiments and analyze data. 6. Must be detail orientated and have demonstrated time management skills. To apply please visit http://www.imclone.com/careers_imclone.php,Requisition #225337. http://www.newscientistjobs.com/jobs/job/associate-scientist-iiscientist-i-md-maryland-200645868.htmFri, 20 Nov 2009 19:16:57 +0000197423My company shares my passion for helping to improve human health around the world.” “This is My MedImmune.” Those who join MedImmune feel a sense of ownership about their future. They thrive with a recognized leader in the biotechnology industry and the wholly-owned subsidiary of AstraZeneca plc. Here, you will join passionate professionals who advance science, technology and medicine to develop products designed to help people live better lives. You will excel in an environment characterized by respect, integrity and growth opportunities…that encourages both individual contribution and collaborative entrepreneurial thinking. Our products and/or product candidates are designed to address areas of need in infection, oncology, respiratory disease and inflammation, cardiovascular/gastrointestinal disease and neuroscience. Explore a MedImmune career as we strive to better more lives, more often, around the world. Title: Associate Scientist II/Scientist I Location: CA, Mountain View - NON SALES Req: 02056 Position Summary: Major Duties and Responsibilities (including supervising others): We are seeking a highly motivated independent individual to join our formulation team aimed at formulation development for biologics including protein and live viruses. The individual will be working with the team focusing on formulation studies and characterizations for liquid or solid dosage formulations. The essential responsibilities will include planning and executing pre-formulation and formulation studies, developing and performing biophysical, biochemical and biological analyses. An ability to work independently and have effective organization and communication skills is essential. Special Skills/Abilities: Expertise in pre-formulation and formulation of proteins and antibodies required. Hands on expertise in analytical techniques including HPLC-SEC, RP-HPLC, FTIR, fluorescence assays, DSC/mDSC are required. A prior experience in ajuvant formulation development is a plus. Experiences with solid state analyses such as Karl-Fischer, TGA, DVS, particle sizing desired. Excellent oral and written skills required. Job Complexity: Medium-High. JOB REQUIREMENTS: Supervision: Work is performed with minimal supervision. (supervision required, level of independence) Requirements/Qualifications: Education: Degree in Chemistry, Chemical Engineering, Pharmaceutical Sciences, Biochemistry, Biophysics. Experience: Ph.D. + 0-3 yrs, M.S. + 8-10 yrs, B.S. + 10-13 yrs. If you are interested in this position please click the Apply Now button below. Req #. 02005 MedImmune is an Equal Opportunity Employer and does not discriminate on the basis of race, color, religion, gender, age, national origin, disability, veteran status, or any other characteristic protected by federal, state or local law. http://www.newscientistjobs.com/jobs/job/postdoctoral-positions-with-interest-in-protein-structure-function-high-ca-california-200633780.htmFri, 20 Nov 2009 16:29:31 +0000196993Postdoctoral position(s) are immediately available for candidates with interest in protein structure-function, high density lipoproteins (HDL), or lipid metabolism. The focus of our group is on HDL, namely HDL metabolism and the structure -function of HDL's main protein component, apolipoprotein A-I. We are leaders in the field of apolipoprotein structure-function, utilizing this understanding to describe the role of HDL in the prevention of atherosclerosis and towards the improvement of hydrophobic drug delivery. Projects include examination of cellular and physiological processes that govern HDL biogenesis, characterization of genes involved in HDL formation and cholesterol mobilization, analysis of apolipoprotein structure, functional analysis of structural features of apolipoproteins, and investigation into the effect of incorporation of hydrophobic drugs onto HDL. Experience in cell biology, protein chemistry and/or lipid metabolism is encouraged. Position qualifications: The candidate should have completed a PhD, MD or PhD/MD and be available to relocate to the SF Bay Area. Emphasis will be placed on candidates with a background in protein chemistry, genetic analysis, RNA knockdown, o fluorescence microscopy. Furthermore, those with history of team-work and group coordination will be prioritized. PHYSICAL REQUIREMENTS: Sit: Up to 8 hours/day Stand/Walk: Up to 6 hours/day Bend/Stoop: Up to 6 hours/day Reach: Up to 6 hours Rep Use of UE/Grasp: Up to 8 hrs Lift/Push/Pull: 25lbs, over 25# with assistance or equipment This job requires the ability to hear alarms clients and/or instruction. The ability to see accurately from 20 inches to 20-ft. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential function of this position. TO APPLY CLICK APPLY NOW BELOW AND REFERENCE POSITION 5262 http://www.newscientistjobs.com/jobs/job/post-doctoral-position-tawbi-laboratory-pa-pennsylvania-200638752.htmMon, 16 Nov 2009 17:07:48 +0000186808Post Doctoral Position- Tawbi Laboratory Applications are requested for a full time, postdoctoral position in the laboratory of Dr. Hussein Tawbi, Division of Hematology/Oncology, Hillman Cancer Center, University of Pittsburgh Cancer Institute. Dr. Tawbi’s laboratory studies the epigenetic regulation of DNA repair and mechanisms of post transcriptional regulation of genes associated with chemotherapy resistance. The successful applicant will be expected to have both the ability and motivation to be a major contributor to the lab’s research program. The project will involve the use of the following techniques: cell culture, RT-PCR, RNA expression, proteomics, immunohistochemistry and siRNA. These studies are primarily conducted in cell culture systems, in vivo, as well as tumor tissue, and require techniques in molecular biology and biochemistry. Candidates must hold a Ph.D in Cell Biology, or Molecular Biology. Experience with procedures on tissue culture and molecular biology methodologies are highly desirable. Excellent verbal and written communication skills are required. Dr. Hussein Tawbi M.D., M.Sc., Assistant Professor of Medicine http://www.newscientistjobs.com/jobs/job/senior-principal-scientist-ca-california-200639965.htmSat, 14 Nov 2009 11:50:04 +0000184789As a member of the Chemistry team, this position requires a broad base of skills in the synthesis, purification and analysis of peptides and organic compounds. Major responsibilities will include: * Interface and communicate project progress with other Pfizer research sites * Recommend biologic target and research program prioritizations * Lead cross functional project teams * Manage internal chemistry project efforts * Independently design and optimize drug candidates * Synthesize and characterize peptides, modified peptides and small molecules as needed * Develop methods for analysis and characterization of peptides and small molecules * Generate reports to support ongoing research and development projects * Assist with the scale-up of peptides and drug candidates as needed * Interface with other functions including development, biology, legal and CROs * Assist in building chemistry organization * Travel as required (foreign and domestic) * Other duties and special projects as required Qualifications: * PhD in organic or medicinal chemistry with 10-15 years relevant industrial experience * Prior experience with structure or pharmacophore based drug designed and familiarity with design of lead molecules and their modification required * Extensive laboratory experience in the characterization and purification of peptides and organic compounds * Demonstrated problem-solving, communication and scientific track records * Peptide drug design experience desirable * Prior supervisory experience required * Applicant should be able to conduct self-directed research and development, and provide technical leadership * Solid written and oral communication skills, enthusiasm, integrity, self-motivation, strong interpersonal skills, and ability to act as a team player are necessary Throughout our 153 years, a legacy of caring for others has been at the heart of everything we do at Pfizer. This commitment is no less important when it comes to our employees. Pfizer wants to ensure that employees have resources to help them develop and succeed both in their careers and personal lives. One way we can achieve this is through our comprehensive benefits program, which offers employees and their eligible dependents the variety and flexibility to help address their needs at different stages in life. Pfizer Inc: Working together for a healthier world Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visa, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residence and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer. HOW TO APPLY: Please copy and paste the following URL into your browser address bar: http://posttrak.arbita.net/cgi-bin/PostTrak.cgi?RefCode=R4944125807953 http://www.newscientistjobs.com/jobs/job/life-sciences-initiatives-seven-faculty-positions-massachusetts-ma-massachusetts-200639787.htmFri, 13 Nov 2009 19:56:08 +0000183725WORCESTER POLYTECHNIC INSTITUTE Life Sciences Initiative Seven Faculty Positions Worcester Polytechnic Institute (WPI) in Worcester, Mass., is continuing a major investment in the life sciences. In 2007 the university opened the WPI Life Sciences and Bioengineering Center (LSBC), which houses the life sciences-related graduate research programs of five academic departments and the WPI Bioengineering Institute (BEI). Since that time, WPI has recruited 12 new full-time faculty members in the life sciences and bioengineering, bringing to more than 30 the number of faculty working in interdisciplinary clusters within a strongly collaborative environment in the LSBC. As a result of this investment, graduate research and external research funding have increased considerably, with faculty awarded major funding from the NIH, NSF, DARPA, and other agencies. In 2008-09 WPI recruited five new full-time life science and bioengineering faculty members across five departments, including a new head for the Biomedical Engineering Department. In 2009-10 we are seeking to fill seven tenure-track positions at the junior and senior levels in five departments, including a new head for the Chemistry and Biochemistry Department. The ideal candidates for these positions will have research interests and expertise that are complementary to our current research areas, and be committed to collaboration among multidisciplinary teams and to securing external funding. Applicants for department head and senior positions will be recognized leaders in their field and have a strong record of securing extramural funding. Applicants at the assistant professor level must have postdoctoral research experience with extramural support, or strong promise to obtain funding. All applicants must hold the PhD and have a strong commitment to teaching at the undergraduate and graduate levels. To apply, and for more on the WPI Life Sciences Initiative, including detailed position descriptions, visit wpi.edu/+lsi. Founded in 1865, WPI is one of the nation’s oldest and most innovative technological universities. Its 14 academic departments offer more than 50 undergraduate and graduate degree programs, including the PhD, in science, engineering, management, and the liberal arts. WPI offers a smoke-free environment, competitive compensation, and an excellent benefits package. To enrich education through diversity, WPI is an affirmative action, equal opportunity employer. It is a member of the Colleges of Worcester Consortium. Chemistry and Biochemistry • The Department of Chemistry and Biochemistry invites applications for a DEPARTMENT HEAD, who will also hold an endowed professorship. The new head will have a clear and creative vision for building and sustaining ambitious departmental research programs during a period of growth. This vision will include enhancing the department’s role in the natural sciences. Contact: Applications and nominations should be sent to cbcheadsearch@wpi.edu. Further inquiries should be directed to the chair of the search committee, Professor Richard Sisson, sisson@wpi.edu, or the head of Chemistry and Biochemistry, Professor Kristen Wobbe, kwobbe@wpi.edu. The department also seeks an ASSISTANT PROFESSOR working in either biochemistry or chemistry. Contact Professor George Kaminski at faculty-searchCBC@wpi.edu. Biology and Biotechnology • The Department of Biology and Biotechnology invites applications for a position at the ASSISTANT PROFESSOR level. Areas of particular interest include ecology and environmental biology, cell and developmental biology, and systems biology. Contact: Professor Eric Overström, head, Department of Biology and Biotechnology, faculty-searchBBT@wpi.edu. Biomedical Engineering • The Department of Biomedical Engineering invites applicants for two positions, one at the ASSISTANT PROFESSOR level specializing in biosignals and bioinstrumentation and one at the ASSOCIATE or FULL PROFESSOR level specializing in regenerative medicine. Contact: chairs of either the Regenerative Medicine or Instrumentation Search Committees at faculty-searchBME@wpi.edu. Mathematical Sciences • The Department of Mathematical Sciences invites applications for a position at the ASSISTANT PROFESSOR level. Applications from candidates with teaching and scholarly interest in the areas of biostatistics, computational statistics, experimental design, or Bayesian methods are especially encouraged. Contact: Math Search Committee, ma-chair@wpi.edu. Physics • The Department of Physics invites applications for a position at the ASSISTANT PROFESSOR level in theoretical or experimental softcondensed matter physics. This position will complement the university’s research initiative in biophysics and regenerative biosciences. Contact: Professor Germano Iannacchione, head, Department of Physics, at ph-search@wpi.edu. http://www.newscientistjobs.com/jobs/job/fellowships-for-postdoctoral-scholars-ma-massachusetts-200639786.htmFri, 13 Nov 2009 19:35:49 +0000183724New or recent doctoral recipients with research interests associated with the following are encouraged to submit scholarship applications prior to January 15, 2010. Departments - Awards related to the following areas are anticipated: Applied Ocean Physics & Engineering; Biology; Geology & Geophysics; Marine Chemistry & Geochemistry; Physical Oceanography Institutes - Each of the following Institutes, which foster interdisciplinary research addressing critical issues, will award a scholarship to support related research: Ocean and Climate Change Institute; Coastal Ocean Institute; Deep Ocean Exploration Institute; Ocean Life Institute The NOAA-WHOI Cooperative Institute for the North Atlantic Region (CINAR) will award a Fellowship in one of five theme areas: Ecosystem Forecasting, Ecosystem Monitoring, Ecosystem Management, Protection and Restoration of Resources, Sustained Ocean Observations and Climate Research. Awards are competitive, with primary emphasis placed on research promise. Scholarships are for 18-months with an annual stipend of $56,000, a modest research budget and eligibility for group health and dental insurance. Recipients are encouraged to pursue their own research interest in association with resident Scientific and Senior Technical Staff. Communication with potential WHOI advisors prior to submitting an application is encouraged. Further information, application forms, and links to the Individual Departments, institutes and Centers and their research themes may be obtained at: http://www.whoi.edu/postdoctoral or by ontacting the Postdoctoral Fellowship Committee at: (508) 289-2219, or postdoc@whoi.edu. An Equal Opportunity/Affirmative Action Employer http://www.newscientistjobs.com/jobs/job/director-nutritional-science-innovation-nj-new-jersey-200635182.htmTue, 10 Nov 2009 14:52:09 +0000177085This role within Nutritional Science will support the activities of Strategic Innovation within Nutritional Sciences. Primary responsibilities are to provide leadership for Nutritional Science in establishing and maintaining a competitive scientific understanding of Centrum and Caltrate brands. Tasks include competitive assessment nutrient profiles to competitor’s (compelling comparisons); support to assigned technology platforms; support to selected clinical studies (ie NIH trials; internally-funded or IIS study oversight). This role will serve as a resource/liaison for the department in the scientific fundamentals for our core brands, and improve Global Clinical & Medical Affairs ability to be responsive to the innovation needs of the business.Establish recommendations for leveraging existing data to build brand messaging and support market growth. Lead bridging strategy meetings (agendas and meeting minutes), interface with external experts, and issue reports summarizing medical POV and action plans for bridging data. Develop compelling comparisons for Centrum and Caltrate brands. Comparison to the top 2-3 competitors in key regional markets: US, Europe, Latin America and Pacific Rim. Develop plan for educating/communicating scientific advantage of brands to affiliate Medical and Marketing teams Develop scientific rationale for key technology platforms. Propose a research strategy for brands to be competitive in these technology areas. Manage the Clinical Claims Task Force – schedule meetings, develop and issue agendas and meeting minutes; track issues and highlight activities quarterly. Serve as consultant to Nutritional Science team on areas of expertise. Mentor and advise on project and claims strategies Qualifications: PhD in science with strong knowledge in nutrition with a mininum of 10 years of experience in a leadership position. Throughout our 153 years, a legacy of caring for others has been at the heart of everything we do at Pfizer. This commitment is no less important when it comes to our employees. Pfizer wants to ensure that employees have resources to help them develop and succeed both in their careers and personal lives. One way we can achieve this is through our comprehensive benefits program, which offers employees and their eligible dependents the variety and flexibility to help address their needs at different stages in life. Pfizer Inc: Working together for a healthier world™ Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S. HOW TO APPLY: Please copy and paste the following URL into your browser address bar: http://posttrak.arbita.net/cgi-bin/PostTrak.cgi?RefCode=R3681125807950 http://www.newscientistjobs.com/jobs/job/formulation-associate-nj-new-jersey-200628453.htmTue, 10 Nov 2009 14:39:25 +0000177072A leader in therapeutic antibodies, ImClone Systems is committed to advancing oncology care by developing a portfolio of novel targeted biologic treatments designed to address the medical needs of patients with a variety of cancers. Founded 25 years ago, ImClone Systems has a rich culture of biotechnology innovation and leading-edge medical science. Our deep expertise in molecular biology, oncology, genomics and antibody engineering has helped us establish a robust pipeline of products that are in various stages of clinical development and span virtually all major solid tumor types. The Formulation Associate will be responsible for assisting in the development of formulations for protein therapeutics, to include buffer preparation, stability studies and investigations for compatibility and delivery problems. ESSENTIAL DUTIES AND RESPONSIBILITIES 1. Operation of Spectrophotometer, pH meter, Conductivity Meter and Electrophoresis Apparatus (i.e. SDS-PAGE, IEF) 2. Operation of analytical HPLC (SEC, IEC and RP) 3. Assists in the development of analytical methods for protein analysis 4. Buffer preparation 5. Perform routine assays to test the chemical stability of proteins in relation to excipients and storage conditions 6. Data entry 7. Assay development and trouble shooting 8. Assist in the development of final drug dosage forms 9. Maintain Laboratory and Laboratory Records 10. Work in a safe manner and be compliant to ImClone Systems policies and procedures ESSENTIAL KNOWLEDGE, SKILLS, EXPERIENCE 1. BS with 2-6 years of experience, MS with 1-4 years of experience 2. Knowledge of the use of and experience with spectrophotometry, electrophoresis (SDS-PAGE and IEF), HPLC. 3. Knowledge of protein chemistry with experience in protein sample analysis and handling. 4. Knowledge and experience in buffer preparation. 5. Knowledge of and operation of biophysical analytical instrumentation will be a plus (Fluorimeter, DSC, HIAC, DLS and Osmometer). http://www.newscientistjobs.com/jobs/job/patent-attorney-chemistry-ma-massachusetts-200631505.htmThu, 05 Nov 2009 09:09:04 +0000169198This position will manage, direct and leverage designated patent and related intellectual property (IP) activities within NIBR. Primary responsibilities will include: .Identify, draft, file and prosecute patent applications for all inventions arising from NIBR projects: technologies, biological targets, New Chemical Entities, secondary patents (e.g., additional indications, combinations). .Take active responsibility for the patent portfolio of all technologies, targets and projects through to NIBR/Pharma transfer. .Formulate patent strategies for key NIBR clients, including the Disease Areas, Early Biology Platforms, and Global Discovery Chemistry that secure target and technology Freedom-to-Operate (FTO), enable IP defense(s) and which could contribute to future product protection. .Direct outside council prosecution and opinion services .Proactively provide critical IP perspective on key decision-making bodies at NIBR. .Provide IP support to Strategic Alliances, including IP strategies leading to transaction opportunities, evaluation of in-licensing opportunities, negotiation support, contract drafting during active transactions; with Head of NIBR IP and Strategic Alliances explore options for development candidates failing to transition into full clinical development or failing prior to Phase III. .Define product-supporting strategies with Pharma patent attorneys prior to NIBR/Pharma transfer; support product strategies of GPTs and Business Franchises/Business Units following NIBR/Pharma transfer as needed. .Conduct target clearance/patent audits at appropriate stage gate consistent with NIBR Patents guidelines; coordinate with corresponding Pharma attorney. .Direct the NIBR IP Search & Analytics team to provide integrated search support NIBR Disease Areas, Biology Platforms, and Global Discovery Chemistry. .Persistently partner, challenge and counsel NIBR clients on opportunities to protect their inventions. .Maximize effective communication with NIBR scientists and leadership. .Timely review of assigned external publication requests. http://www.newscientistjobs.com/jobs/job/manager-regulatory-cmc-nj-new-jersey-200618969.htmWed, 04 Nov 2009 15:14:24 +0000167848A leader in therapeutic antibodies, ImClone Systems is committed to advancing oncology care by developing a portfolio of novel targeted biologic treatments designed to address the medical needs of patients with a variety of cancers. Founded 25 years ago, ImClone Systems has a rich culture of biotechnology innovation and leading-edge medical science. Our deep expertise in molecular biology, oncology, genomics and antibody engineering has helped us establish a robust pipeline of products that are in various stages of clinical development and span virtually all major solid tumor types. The Manager, Regulatory CMC is responsible for maintaining competent knowledge of current / emerging regulations, guidance documents and corporate/industry standards, with an ability to evaluate same for impact on tactical operations. Good technical knowledge, provides committed, value-added effort in support of development projects and approved products. Must be detail-oriented with good oral and written communications skills; able to prepare accurate, clear and concise regulatory documents and manage the quality review process. Excellent time management skills essential; must be able to multi-task and drive timelines for deliverables. The position is primarily tactical however strategic insight is required. ESSENTIAL DUTIES AND RESPONSIBILITIES: 1. Will have an in-depth understanding of regulatory CMC requirements, including FDA, EMEA, ICH guidelines and relevant government regulations (21 CFR, EU Directive). 2. Reviews websites and develops initial impact assessment of draft regulatory guidance, communicating changes in regulatory requirements to senior regulatory management. 3. Provides regulatory guidance to ensure development activities are compliant with relevant regulations and in line with current global guidance. 4. Communicates regulatory strategy and guides manufacturing in developing data for approval of post-marketing changes. 5. Works with development teams and Regulatory Operations to outline submission requirements and negotiate timelines for regulatory CMC submissions. 6. Prepares the CMC section of INDs, BLAs, CTAs, CTDs, amendments, supplements and annual reports, including the compilation and review of the required data, scientific reports, and written submission contributions. 7. Reviews and assesses the regulatory impact of all change controls/requests for the manufacture, testing and release of development and marketed products. 8. Assists in the implementation of processes and applications to support regulatory activities ESSENTIAL KNOWLEDGE, SKILLS, EXPERIENCE: 1. Must have 3 – 5 years of pharmaceutical industry experience including a minimum of 2 years of regulatory or related experience. 2. Demonstrated knowledge of the drug development process and government regulations/guidelines, including US and international product registration. 3. Good oral and written communication skills with a focus on accuracy (vigilant attention to detail) and clarity are essential. 4. Ability to supervise and mentor junior staff members. 5. BA/BS degree or equivalent experience. http://www.newscientistjobs.com/jobs/job/national-exposure-research-laboratory-post-doctoral-research-program-united-states-200629355.htmTue, 03 Nov 2009 23:03:06 +0000166272• The National Exposure Research Laboratory (NERL) of the United States Environmental Protection Agency is accepting applications beginning November 2, 2009 through January 11, 2010 for approximately 10 federal, three-year post-doctoral research positions. • Candidates will engage in research in areas such as: computer modeling of the transport, transformation, and fate of pollutants in multiple media and at multiple scales, hydrologic modeling, GIS mapping and interpretation for human exposure, demographics related to ecological exposure, modeling of microbial fate and exposure, and exposure modeling for epidemiological studies. • Specific research opportunities are posted on the NERL website at http://www.epa.gov/nerl • Post-doctoral positions will be in one or more of the following locations: Research Triangle Park, North Carolina; Cincinnati, Ohio; Las Vegas, Nevada; or Athens, Georgia. FULL FEDERAL EMPLOYMENT BENEFITS • Salary range of $67,613 - $91,305 (subject to increase in January 2010) • Full three-year appointments • Paid relocation to EPA duty location • Vacation and sick leave • Federal health benefits, life insurance, and retirement program • Travel to professional and scientific meetings • Flexible start date beginning in March/April and no later than September 2010 APPLICATION PROCESS – Consult the NERL website at http://www.epa.gov/nerl for instructions on how to apply. Note – online applications from journal websites are not accepted. Applicants must provide: • Up-to-date Curriculum Vitae • Letter of recommendation from your research advisor or comparable official • Cover letter indicating: o positions and locations of interest o your email address o U.S. Citizenship status, AND o How you learned of this program (If you first learned of the program at an online website, please provide name of website.) • DD-214, if claiming veteran’s preference • Applicants must be United States citizens or permanent residents. Only in the absence of qualified U.S. citizens will permanent residents who are citizens of countries specified as exceptions to the appropriations act ban on paying non-U.S. citizens be considered. Specific job information is posted on the NERL Internet site at http://www.epa.gov/nerl. EPA provides reasonable accommodations to applicants with disabilities. If you need a reasonable accommodation for any part of the application and hiring process, please notify the Agency. The decision on granting reasonable accommodation will be on a case by case basis. The U.S. EPA is an Equal Opportunity Employer http://www.newscientistjobs.com/jobs/job/director-process-dev-mgmt-ca-california-200627247.htmMon, 02 Nov 2009 04:27:09 +0000163162Responsibilities: The Protein Analytical Chemistry Department in Genentech's Quality Bioanalytical Development organization has a Director-level opportunity for an accomplished analytical scientist to lead a talented and dedicated department. She/he will need to be able to develop strategies and influence internal and external practices regarding analytical characterization, method development and validation, and method transfers to testing groups. This leader will also play a key role in regulatory negotiations. The successful candidate will need to establish and maintain important internal collaborations with other functions, including research, bioprocessing, quality, regulatory, and pharmaceutical development. She/he will also need to be able to identify emerging analytical technologies, and be able to oversee the department's efforts to convert new technologies into mainstream approaches in PAC and associated departments. Requirements: The successful candidate will have a Ph.D. in chemistry, biochemistry, or a related area with 10+ years of analytical protein chemistry experience and 5+ years leading scientist-level staff and/or cross-functional teams. This person will also have a track record of accomplishment in translating innovative science into successful analytical strategies, and relevant experience managing a business unit. This position requires demonstrated evidence of the candidate's ability to hire, develop and manage a staff of approximately 30 RAs and Scientists  Experience with conjugated proteins and contract laboratories will be a plus. This leader must understand process development strategies and clinical GMP requirements.   DIVISION:  Process Dev & New Manuf Facil REQUISITION NUMBER:  09-1000028872 http://www.newscientistjobs.com/jobs/job/assoc-dir-process-dev-mgmt-ca-california-200627243.htmMon, 02 Nov 2009 04:26:32 +0000163159Associate Director - Drug Delivery Development Responsibilities The successful candidate will lead a group of scientists and engineers to develop and commercialize drug delivery systems for Genentech's therapeutic proteins in conjunction with external partners.  Drug delivery systems may include sustained release, CNS and oral delivery systems.  Major responsibility will include technical oversight for all phases of feasibility assessment, development and commercialization of the delivery systems performed both in house and by external partners.  The candidate will serve as a key resource and provide input to Research, Development, Marketing, Technical Operations and Regulatory on development strategy for project teams. The individual will also be responsible to develop and maintain the drug delivery technology portfolio for Process R&D, including budget responsibilities. Requirements The ideal candidate will have a Ph. D in Chemical Engineering, Material Sciences, Pharmaceutical Sciences or a related field.  Experience in the Pharmaceutical or Drug Delivery industry is required, with at least 10 years of experience in drug delivery, and/or pharmaceutical development.  Prior experience with protein delivery systems is preferred.   A proven track record of working effectively in a highly cross-functional and collaborative environment is highly desirable. Excellent people management, communication and influencing skills are required. DIVISION:  Process Dev & New Manuf Facil REQUISITION NUMBER:  09-1000028305 http://www.newscientistjobs.com/jobs/job/assoc-scientist-ca-california-200627239.htmMon, 02 Nov 2009 04:25:33 +0000163156Associate Scientist/Scientist, Drug Delivery Systems Genentech's Early Stage Pharmaceutical Department is looking for a scientist with a background in chemical engineering, material science or polymer chemistry with application to the design and evaluation of drug delivery systems to fill a position within their inter-disciplinary Drug Delivery group. In this newly created position, you will provide expertise in the area of polymer chemistry or material sciences to evaluate external protein drug delivery technologies as well as contribute to internal delivery efforts. In Genentech's team oriented environment, you will collaborate across functional areas to provide and analyze the performance of delivery technologies for in vitro release rates, impact on the delivered protein, ability to manufacture and biocompatibility. You will participate in due diligence evaluations of delivery technologies suitable for pipeline needs and provide expertise to facilitate the incorporation of delivery technologies into product development of selected projects. You will present concepts/findings to our review committees, author technical reports, publications, as appropriate, and submission of patent applications and regulatory filings. Requirements: Qualified candidates must have a technical background in chemistry, biochemistry, polymer chemistry or material sciences with a Ph.D. in Polymer Chemistry, Materials Science, Chemical Engineering or a related field with or without post-doctoral experience. Prior experimental experience with protein delivery systems is a strong plus, particularly in assessing technical feasibility and manufacturability of delivery systems. Candidates must have effective oral and written communication skills, strong interpersonal and collaborative skills and the demonstrated ability to drive for results. DIVISION:  Process Dev & New Manuf Facil REQUISITION NUMBER:  09-1000027367 http://www.newscientistjobs.com/jobs/job/assoc-director-quality-ca-california-200627236.htmMon, 02 Nov 2009 04:24:50 +0000163153Associate Director, Quality Bioanalytical Development Method Validation There is an Associate Director position available in Protein Analytical Chemistry, a part of Genentech's Quality Bioanalytical Development organization, to an accomplished individual with experience in method validation for commercial filings.  The responsibilities of this individual will include leading a group to oversee method validation for licensure of new products, developing efficient approaches to phase appropriate method qualification and validation, and ensuring compliance with GLP/GMP requirements and Genentech Quality Systems. The successful candidate will have a Ph.D. (or equivalent) in chemistry, biochemistry, or a related area with 10+ years experience in a protein therapeutics Quality Control environment.  She/he must have demonstrated a solid understanding of GMP requirements for method validation and testing for US and European regulatory filings to support clinical development and licensure.  S/he must have the ability to develop, execute and defend phase-appropriate validation strategies.  Strong managerial skills are required, including hiring and developing staff.   The successful candidate is expected to exhibit strong teamwork and collaborative skills with outstanding verbal and written communication. DIVISION:  Process Dev & New Manuf Facil REQUISITION NUMBER:  09-1000028363 http://www.newscientistjobs.com/jobs/job/assistant-associate-or-senior-scientists-benthicseafloor-biogeochemistry-ma-massachusetts-200627036.htmFri, 30 Oct 2009 22:32:09 +0000161576The Marine Chemistry & Geochemistry Department at the Woods Hole Oceanographic Institution (WHOI) invites applications for one or more tenure-track or tenured positions at the level of Assistant, Associate or Senior Scientist in the field of Benthic or Seafloor Biogeochemistry. Areas of interest include seafloor microbe-mineral interactions at and below the seafloor, the biogeochemical cycling of carbon, nutrients and trace elements in sedimentary and crustal environments, and chemical fluxes and fluid flow between sediments and the ocean crust, and between sediments and the oceanic water column. Candidates with an interest in the development of novel in situ and laboratory-based measurement techniques are particularly encouraged to apply. WHOI is a private non-profit research organization that offers exceptional research and educational opportunities. The selected individual(s) would have the opportunity to work closely with WHOI scientists and engineers carrying out research in the fields of chemical, biological, geological and physical oceanography, and participate in shaping an interdisciplinary climate research program at WHOI. Information regarding on- going research at WHOI can be found at www.whoi.edu. The successful applicant(s) will be expected to have a strong interest in collaborative research, seek funding to establish a productive research program, and contribute to graduate education within the MIT/WHOI Joint Program in Oceanography/Applied Ocean Science and Engineering. The candidate should submit a current CV, a short (1-3 page) Research Statement, and the names of four potential references along with her/his on-line application. The level of the appointment will be based on credentials and experience. Review of applications will begin on December 1, 2009. For information on the Department of Marine Chemistry and Geochemistry, other WHOI departments, centers and facilities, the MIT/WHOI Joint Program, the WHOI Ocean Institutes and the Woods Hole Consortium of research organizations, please visit the following websites: WHOIMarine Chemistry and Geochemistry Department http://www.whoi.edu/MCG/ WHOI Physical Oceanography Department http://www.whoi.edu/PO/ WHOI Geology and Geophysics Department http://www.whoi.edu/GG/ WHOI Ocean and Climate Change Institute http://www.whoi.edu/OCCI/ TheMIT/WHOI Joint Program http://web.mit.edu/mit-whoi/www/ TheWoods Hole Consortium http://www.woodsholeconsortium.org/ Applicants should have a doctoral degree, postdoctoral experience and a publication record in benthic / seafloor biogeochemistry, or related fields. Women and minority applicants are particularly encouraged, and WHOI is sensitive to the issues of dual career scientists and will work with applicants to address them. WHOI is sensitive to the issues of dual career scientists and will work with applicants to address them. Please visit our site by clicking Apply Now for a detailed job description and to apply online today! WHOI is an Affirmative Action/Equal Opportunity Employer M/F/D/V. Applications are reviewed confidentially. http://www.newscientistjobs.com/jobs/job/assistant-associate-or-senior-scientist-multiple-openings-ma-massachusetts-200627039.htmFri, 30 Oct 2009 22:30:58 +0000161577The Department of Applied Ocean Physics and Engineering at theWoods Hole Oceanographic Institution (www.whoi.edu/aope) invites applications for tenure track faculty positions.We seek exceptional candidates to expand and complement our existing observational and theoretical strengths in coastal ocean fluid dynamics, ocean acoustics, and underwater vehicles. Target research topics this year include (but are not restricted to): • AUV and glider technologies for chemical, acoustic, and other sensing applications (including MEMS and micro-fluidic sensors) • Computational methods in ocean acoustics • Remote sensing of coastal processes • Signal processing and machine learning (including autonomous recognition and decision making) for ocean applications • Physical-biological interactions at scales from individuals to ecosystems Candidates are expected to develop independent, externally funded, and nationally and internationally recognized research programs. Faculty members have the option of advising graduate students and teaching courses through the MIT/WHOI Joint Program in Oceanography and Oceanographic Engineering. Opportunities for interdisciplinary research exist through collaboration with the other science departments (www.whoi.edu/departments) and research institutes (www.whoi.edu/institutes) at WHOI. Applicants should have a doctoral degree, postdoctoral experience, and a publication record in their expertise. Education and experience will dictate position level.Women and minority applicants are particularly encouraged to apply.WHOI is sensitive to the issues of dual career scientists and will work with applicants to address them. Successful candidates hired at the Assistant Scientist and Associate Scientist without tenure levels will receive an initial contract for 4 years with salary guaranteed. Qualified candidates should submit their curriculum vitae including a list of publications, a statement of research interests (three page maximum), and names and contact information of four references by January 15, 2010. Please visit our website for a detailed job description and to apply online today! WHOI is an Affirmative Action/Equal Opportunity Employer M/F/D/V. Applications are reviewed confidentially http://www.newscientistjobs.com/jobs/job/postdoctoral-investigator-chemical-oceanography-ma-massachusetts-200627038.htmFri, 30 Oct 2009 22:25:41 +0000161575The Marine Chemistry and Geochemistry Department is searching for a Postdoctoral Investigator to join their team. The initial appointment is for 18 months with the possibility of extension. Job Summary: Examine processes relating to trace metal transport at the land-ocean margin. Trace metal sources and pathways will be investigated using radium isotopes. The successful applicant will conduct field studies both land based and at sea. Experience with radiochemical counting techniques and/or trace metal analyses via ICP-MS is highly desired. Education Desired: Ph.D. degree in Chemical Oceanography or related discipline is required. Applicants should have fluent written and oral communication skills in English. Please submit a statement of research interests (2-3 pages), C.V., and a list of three references with complete contact information. **Applications will be reviewed starting on May 1st and will continue until the position is filled** If you are an interested candidate, there is a two-step process to apply for this position. You will not finish the application process until BOTH Steps 1 and 2 are completed: Step 1: Please submit your curriculum vitae (including a list of publications), statement of research interests, and the names and addresses (including email addresses) of 3 references along with your application by clicking Apply Now Please be sure to reference the announcement number; Job Reference 09-03-03 Step 2: Complete an online application on http://jobs.whoi.edu/