http://www.newscientistjobs.com/jobsNew Scientist Jobshttp://www.newscientistjobs.com/jobs/job/senior-research-associate-philadelphia-pa-pa-pennsylvania-200631302.htmFri, 20 Nov 2009 22:08:16 +0000196398Senior Research Associate, Philadelphia, PA No relocation! For consideration, applicants must be located near the Philadelphia, PA area. Description: Under the direction of the Director of the Immunology Laboratory, to promote and coordinate the multiple aspects of the growing research program of immunology Laboratory. The job involves performing diverse and complex clinical research activities including, but not limited to, writing study protocols and other research related documents, maintaining IRB and GCRC approval of study protocols, creating and instituting quality assurance procedures, performing research quality bone age and bone mineral density determinations, data management and quantitative analysis, collaborating in developing innovative research and educational programs, writing manuscripts and grant proposals, coordinating activities in multi-center studies, and serving as an educational resource for the laboratory and the Institution. This position has the potential for the candidate to develop into an independent investigator. Qualifications: MD or Ph.D. or equivalent in Immunology or related field with 2 years of experience in pediatric stress/psychometric biomarkers. Previous experience in cell culture, Elisa and PCR preferred. Ability to function independently in a clinical research setting. Excellent writing skills. Excellent communication skills to interact with staff, parents and children. Ability to handle confidential materials. Ability to handle multiple, time dependent tasks. Excellent organizational skills. Ability to use computers, learn new software applications. Ability to manage data and perform quantitative analysis. Ability to write progress reports and scientific manuscripts. To apply please send your CV and three letters of recommendation to Wendy Rochlin by clicking Apply Now. http://www.newscientistjobs.com/jobs/job/research-associate-iii-ca-california-200645870.htmFri, 20 Nov 2009 19:22:09 +0000196352My company shares my passion for helping to improve human health around the world.” “This is My MedImmune.” Those who join MedImmune feel a sense of ownership about their future. They thrive with a recognized leader in the biotechnology industry and the wholly-owned subsidiary of AstraZeneca plc. Here, you will join passionate professionals who advance science, technology and medicine to develop products designed to help people live better lives. You will excel in an environment characterized by respect, integrity and growth opportunities…that encourages both individual contribution and collaborative entrepreneurial thinking. Our products and/or product candidates are designed to address areas of need in infection, oncology, respiratory disease and inflammation, cardiovascular/gastrointestinal disease and neuroscience. Explore a MedImmune career as we strive to better more lives, more often, around the world. Title: Research Associate I/II Location: CA, Santa Clara - NON SALES Req: 02076 Major Duties and Responsibilities (including supervising others): Development and/or optimization of virus upstream processes (from cell thaw through viral harvest). This includes designing experiments, analyzing data, developing batch records, SOPs and protocols, and writing and/or reviewing technical reports. This may also include the evaluation of alternative methodologies and/or materials for various process operations and steps. Serve as a member of the team responsible for the technology transfer of processes to large scale manufacturing sites. This includes writing and/or review of batch records and contract manufacturing staff, and providing the necessary technical support to the contract manufacturer once the process has been transferred and cGMP manufacturing has begun. Maintenance of upstream process development equipment including bioreactors, cell counters, metabolite analyzers, pumps and gauges. Maintenance of inventory for commonly used lab supplies. Other responsibilities as required by the department or team. JOB REQUIREMENTS: Requirements/Qualifications: Education: B.S. in Engineering Experience: 2-5 years Special Skills/Abilities: Bioreactor operation Job Complexity: Cell culture in Biolevel 2 labs Supervision: Supervision required If you are interested in this position please click the Apply Now button below. Req #. 01889 MedImmune is an Equal Opportunity Employer and does not discriminate on the basis of race, color, religion, gender, age, national origin, disability, veteran status, or any other characteristic protected by federal, state or local law. http://www.newscientistjobs.com/jobs/job/postdoctoral-positions-with-interest-in-protein-structure-function-high-ca-california-200633780.htmFri, 20 Nov 2009 16:29:31 +0000195920Postdoctoral position(s) are immediately available for candidates with interest in protein structure-function, high density lipoproteins (HDL), or lipid metabolism. The focus of our group is on HDL, namely HDL metabolism and the structure -function of HDL's main protein component, apolipoprotein A-I. We are leaders in the field of apolipoprotein structure-function, utilizing this understanding to describe the role of HDL in the prevention of atherosclerosis and towards the improvement of hydrophobic drug delivery. Projects include examination of cellular and physiological processes that govern HDL biogenesis, characterization of genes involved in HDL formation and cholesterol mobilization, analysis of apolipoprotein structure, functional analysis of structural features of apolipoproteins, and investigation into the effect of incorporation of hydrophobic drugs onto HDL. Experience in cell biology, protein chemistry and/or lipid metabolism is encouraged. Position qualifications: The candidate should have completed a PhD, MD or PhD/MD and be available to relocate to the SF Bay Area. Emphasis will be placed on candidates with a background in protein chemistry, genetic analysis, RNA knockdown, o fluorescence microscopy. Furthermore, those with history of team-work and group coordination will be prioritized. PHYSICAL REQUIREMENTS: Sit: Up to 8 hours/day Stand/Walk: Up to 6 hours/day Bend/Stoop: Up to 6 hours/day Reach: Up to 6 hours Rep Use of UE/Grasp: Up to 8 hrs Lift/Push/Pull: 25lbs, over 25# with assistance or equipment This job requires the ability to hear alarms clients and/or instruction. The ability to see accurately from 20 inches to 20-ft. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential function of this position. TO APPLY CLICK APPLY NOW BELOW AND REFERENCE POSITION 5262 http://www.newscientistjobs.com/jobs/job/laboratory-technician-london-200644774.htmFri, 20 Nov 2009 11:04:08 +0000194274Grade 6 Full Time A dedicated individual is required to assist the gene therapy team in the day to day running of the cellular therapies facility and compliance with clinical trial regulations. The team are based in the Molecular Immunology Unit at the UCL Institute of Child Health. The post holder will be responsible for organising stock control, premises and equipment maintenance, environmental monitoring and arranging in process QC tests. In addition, the role will include supporting the gene therapy team in the translation of new procedures from research to the clinical setting, conducting the cell manipulations for the trials and performing patient monitoring assays to assess efficacy and safety of the treatment. The position provides an opportunity to become involved in cutting edge research at the interface between science and clinical medicine, in a unit with an excellent track-record in both basic and translational science. The post is funded for 3 years. Applicants must have a BSc (or equivalent) in a relevant subject area. Experience of working in a research or clinical laboratory, ideally with experience of cell culture, flow cytometry or molecular biology. You must have familiarity with the day to day running of a laboratory or clean room facility. Good organisational skills and keen eye for detail is essential. Good communication skills and ability to work in a team or using own initiative is essential. For further details about the vacancy and how to apply on line please click the Apply Now button. If you are unable to apply online please contact ICH Human Resources on k.white@ich.ucl.ac.uk or telephone the number listed within the 'View Contact Details' section below, quoting job reference 1122001 We particularly welcome applications from black and minority ethnic candidates as they are under-represented within UCL at this level. This is in line with section 38 of the Race Relations Act 1976. Closing Date: 2nd December 2009 at 5:00pm Any offer of employment will be subject to a Criminal Record Bureau check. http://www.newscientistjobs.com/jobs/job/research-assistant-institute-of-metabolic-science-cambridge-200644749.htmFri, 20 Nov 2009 10:46:43 +0000194210Metabolic Research Laboratories, Department of Clinical Biochemistry Limit of tenure: 31st March 2012. Applications are invited for a Research Assistant position funded by the Wellcome Trust to start as soon as possible. You will be working on a research study led by Dr. Robert Semple on the molecular characterisation of novel syndromes of abnormal growth and insulin action. Duties will include the management of clinical samples, extraction and handling of protein, RNA/ DNA and facilitating the smooth day-to-day running of a busy lab. You will also be trained in techniques including mutation detection, genotyping, realtime RT-PCR, immunoprecipitation and immunoblotting. Applicants should have a BSc in Biochemistry, Genetics or a related discipline. You will have experience in molecular biology techniques, good communication and teamworking skills, flexibility to meet deadlines and the ability to work independently when required. Knowledge of cell culture techniques and interest or previous experience in diabetes and/or cell signalling will be an advantage. Applications, including CV, covering letter, names and addresses of three referees and a completed PD18 form (available by clicking the Apply Now button) should be sent to Dr Robert Semple at the address listed within the 'View Contact Details' section below. Further details may be obtained by e-mailing him at rks16@cam.ac.uk Please quote reference: RG05953. Closing date: 3 December 2009. The University values diversity and is committed to equality of opportunity. http://www.newscientistjobs.com/jobs/job/postdoctoral-fellow-tufts-medical-center-boston-ma-united-states-200642985.htmWed, 18 Nov 2009 18:57:12 +0000190088NIH-funded position available in vascular biology, investigating the role of innate immunity in atheroclerosis. Ph.D in physiology, cell biology, immunology or related field required. Applicant must be a U.S. resident. The successful applicant will: • Conduct research on the role of Toll-like receptors and vascular progenitor cells in arterial disease. • Analyze data and prepare manuscripts for publication. • Assist in preparing and writing grant applications. Skills required: • Proficiency in general laboratory techniques including cell culture, use of transgenic mice, Western Blot analysis, PCR, and ELISA. • Experience in confocal microscopy or flow cytometry are desirable. • Ability to develop new techniques. • 1-2 years experience desirable. Please send CV and a statement of research interests by clicking Apply Now below Debbie Beasley, Ph.D. Associate Professor of Medicine Molecular Cardiology Research Institute Tufts Medical Center http://www.newscientistjobs.com/jobs/job/sallie-rosen-kaplan-fellowship-for-women-in-basic-clinical-epidemiological-or-prevention-science-md-maryland-200564268.htmWed, 18 Nov 2009 18:12:48 +0000190076Sallie Rosen Kaplan Fellowship for Women in Basic, Clinical, Epidemiological or Prevention science National Cancer Institute Sallie Rosen Kaplan Fellowship for Women in Basic, Clinical, Epidemiological Or Prevention Science The Sallie Rosen Kaplan Fellowship for Women Scientists in Cancer Research is made possible by a generous bequest to the Foundation for NIH (FNIH). This is a competitive program for female postdoctoral fellows applying to train in any of the National Cancer Institute’s intramural research settings, including basic, clinical, epidemiological, and prevention science. The postdoctoral fellowship experience at the NCI can serve as a first postdoctoral training assignment, or offer more experienced postdoctoral scientists an opportunity to further their training in more advanced methods, to acquire new research capabilities, to make changes in the direction of their research, or to receive training in fundamental sciences and clinical disciplines for the purpose of enhancing the transfer of biotechnology to cancer clinical programs. Program duration is normally 2 to 5 years. Fellows will be supported by a Cancer Research Training Award (CRTA), with an augmented stipend in the first year provided by the FNIH. The CRTA Fellowship stipend range is $44,600 to $82,400 commensurate with level of experience. Standard self and family health insurance is provided and high option coverage is available. Candidates for the Sallie Rosen Kaplan Fellowship must be female, must possess a doctoral degree, and must have less than 5 years postdoctoral research experience. U.S. citizenship or U.S. permanent residency (green card) is required. Finalists for the Kaplan fellowship will be notified by March 2010 and winners announced by May 2010. To be eligible for the Sallie Rosen Kaplan Fellowship award, the starting date of any NCI fellowship must be no earlier than December 14, 2009. Applicants are required to apply online at http://www.training.nih.gov/apps/publicForms/postdoctoral/forms/adIndex.aspx by December 11, 2009. Additional information about the Kaplan Fellowship can be found at http://www.cancer.gov/researchandfunding/training/srk DHHS, NIH and NCI are Equal Opportunity Employers http://www.newscientistjobs.com/jobs/job/technical-support-specialist-life-science-products-dorset-200642767.htmWed, 18 Nov 2009 15:48:43 +0000189867Company: A Global Lab Supply company Location: South coast, Dorset, Hants, Type: Permanent Division: SCIENTIFIC Reference: LA73.20 Salary: to £32k plus benefits This long established company known globally for supplying cutting edge research products and delivering exceptional levels of service to its customers in the wider scientific community. Based from head office on the south coast, you will make frequent on-site customer visits across the UK providing technical support, training and advice on a range of products essential for life science researchers. You'll develop training materials, write data sheets and keep product info as technically up to date as possible. Also acting as trouble shooter and problem solver you will be the company's expert for this interesting product range. Of degree caliber (preferably higher) in a relevant life science, you have good knowledge of cell signalling and neuroscience and any practical knowledge of immunohistochemical staining and western blotting will be a distinct advantage. This experience probably comes from working in either a protein lab, pharmacology or physiology laboratory. A great opportunity for a start in the commercial world with one of the world's major players! Please note that Helix is a Recruitment Agency and will need to ask candidates if they have a right to work in the UK. http://www.newscientistjobs.com/jobs/job/assistant-professor-and-associate-professor-positions-ma-massachusetts-200641020.htmMon, 16 Nov 2009 19:28:37 +0000185827ASSISTANT PROFESSOR AND ASSOCIATE PROFESSOR POSITIONS MASSACHUSETTS GENERAL HOSPITAL HARVARD MEDICAL SCHOOL DEPARTMENT OF DERMATOLOGY Positions for Assistant Professor and Associate Professor, are available at the Cutaneous Biology Research Center of MGH/Harvard Medical School/Department of Dermatology. Applicants must have a Ph.D. and/or M.D. degree, and a strong interest relevant to cutaneous biology, including but not limited to immunology, chemical biology, epigenetics and clinically oriented skin research. Current faculty members investigate inductive signaling, transcriptional regulation, apoptosis, angiogenesis, carcinogenesis, extracellular matrix function, and appendage development in vertebrate systems. Excellent core facilities and generous start-up funds are available. Interested candidate should send, via email only, curriculum vitae, brief statement of research directions, names, full addresses and emails of three references no later than March 1, 2010. TO COMPLETE THIS APPLICATION CLICK APPLY NOW BELOW The MGH/Harvard Cutaneous Biology Research Center is a committed Equal Opportunity/Affirmative Action Employer. Minorities, women, handicapped, and veterans are encouraged to apply. http://www.newscientistjobs.com/jobs/job/post-doctoral-position-tawbi-laboratory-pa-pennsylvania-200638752.htmMon, 16 Nov 2009 17:07:48 +0000185735Post Doctoral Position- Tawbi Laboratory Applications are requested for a full time, postdoctoral position in the laboratory of Dr. Hussein Tawbi, Division of Hematology/Oncology, Hillman Cancer Center, University of Pittsburgh Cancer Institute. Dr. Tawbi’s laboratory studies the epigenetic regulation of DNA repair and mechanisms of post transcriptional regulation of genes associated with chemotherapy resistance. The successful applicant will be expected to have both the ability and motivation to be a major contributor to the lab’s research program. The project will involve the use of the following techniques: cell culture, RT-PCR, RNA expression, proteomics, immunohistochemistry and siRNA. These studies are primarily conducted in cell culture systems, in vivo, as well as tumor tissue, and require techniques in molecular biology and biochemistry. Candidates must hold a Ph.D in Cell Biology, or Molecular Biology. Experience with procedures on tissue culture and molecular biology methodologies are highly desirable. Excellent verbal and written communication skills are required. Dr. Hussein Tawbi M.D., M.Sc., Assistant Professor of Medicine http://www.newscientistjobs.com/jobs/job/faculty-positions-department-of-pharmacology-chemical-biology-pa-pennsylvania-200638760.htmMon, 16 Nov 2009 17:06:07 +0000185733Faculty Positions University of Pittsburgh School of Medicine Department of Pharmacology & Chemical Biology Applications are invited for tenure-stream Assistant Professor level faculty positions in the Department of Pharmacology & Chemical Biology. Candidates who have a Ph.D., M.D. or equivalent graduate degree are being recruited to expand a strong cadre of faculty. The University of Pittsburgh School of Medicine currently ranks 6th among NIH-funded academic medical centers, and the department is consistently one of the top NIH-funded Departments of Pharmacology. The School of Medicine and the department are executing an exciting vision for both the expansion and integration of basic research, clinical investigation and patient care missions. The department houses state-of-the-art facilities supporting microscopy, mass spectrometry, protein chemistry, gene expression profiling, genetic models of disease, receptor analysis, physiologic monitoring, physical chemistry, organic/combinatorial chemistry and high throughput drug discovery. Successful candidates must have excellent communications skills, develop an outstanding extramurally-supported research program and be committed to the graduate and medical teaching missions of the department. Salary and benefits are highly competitive, with excellent start-up investments available. While all strong applicants will be considered, the Department of Pharmacology & Chemical Biology has significant depth of expertise in cell and organ systems pharmacology, cardiovascular pharmacology, neuropharmacology, endocrinology, cell signaling, cancer biology, DNA damage/repair and drug discovery. Applicants should provide via e-mail a one-page statement of research objectives, curriculum vitae, and contact information for three references by December 31, 2009 to: Bruce A. Freeman, Ph.D. Irwin Fridovich/UPMC Professor Chair of Pharmacology & Chemical Biology University of Pittsburgh, School of Medicine W1340 Biomedical Science Tower Pittsburgh, PA 15261 E-mail: pharmdev@pitt.edu http://www.pharmacology.us/ The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer. http://www.newscientistjobs.com/jobs/job/senior-laboratory-scientist-portsmouth-200639549.htmFri, 13 Nov 2009 16:24:46 +0000182475Pall Corporation is the largest and most diverse filtration, separations and purifications company in the world. We manufacture and market filtration, purification, and separation products and integrated systems solutions worldwide. We operate in five segments: Medical, Bio Pharmaceuticals, General Industrial, Aerospace, and Microelectronics. Our technical expertise, product portfolio and global reach are unmatched. This diversity is a considerable strength. It enables us to leverage opportunities across industries and geographies. Our collective efforts are enabling a greener more sustainable future A Senior Laboratory Scientist is required within the SLS Life Sciences group to generate test data and provide support for R&D projects. The role will entail maintenance and preparation of mammalian cell, insect and bacterial cultures, performance of laboratory test work, biochemical analysis and operation of test rigs to support downstream processing. Duties will include performing cell culture optimisation work, authorising batch records, maintaining laboratory procedures and developing new operating systems within Biologics Services as a manufacturing facility. You will also be required to work in accordance with the principles of Good Laboratory Practice, Health and Safety regulations and possess good communication skills, both written and verbal. Ideally, applicants should be educated to degree level in a Biological Science. To be considered for this role, it is essential that you have cell culture/fermentation laboratory experience as well as the ability to work in a cross departmental team. http://www.newscientistjobs.com/jobs/job/postdoctoral-research-fellow-fl-florida-200639476.htmFri, 13 Nov 2009 15:48:04 +0000182389One fully funded post-doctoral position is available to study the role of tumor suppressor proteins and signaling molecules in cell cycle regulation, oncogenesis, angiogenesis and tumor metastasis. Our laboratory focuses on Rb, E2F and prohibitin genes and how they regulate downstream targets in response to extracellular signals and tobacco carcinogens. Our recent work can be seen in Mol. Cell. Biol., 24, 9527-41; Oncogene, 24, 2204-2217; J. Biol. Chem, 281(5):2951-9; Proc. Natl. Acad Sci, USA. 103 (16) 6332-6337; Mol. Cell. Biol, 26:4161-71; J Clin Invest. 116:2208-17 etc. Our current studies include screening for novel anti-tumor agents that disrupt signal transduction pathways, studying gene regulation in lung cancer and developing transgenic as well as knock-out mouse models for cancer. Applicants should have a recent Ph.D. in molecular biology, cell biology or related fields and be familiar with routine protein and DNA techniques as evidenced by publications. Experience with mammalian systems including tissue culture techniques, transfections and promoter analysis will be a plus. Familiarity with animal models of cancer including transgenic and knock-out mice is desirable. Moffitt Cancer Center is a modern facility on the University of South Florida Campus that conducts research on various aspects of Cancer Biology with emphasis on translational research. Please visit www.moffitt.org/careers to apply online to REQ ID 4835 and send CV and contact information for three references by e-mail to: Dr. Srikumar Chellappan, Professor, Drug Discovery Program, Moffitt Cancer Center, 12902 Magnolia Dr., Tampa, FL 33612. Phone: (813) 745-6892; fax: (813) 745-6748. E-mail: Srikumar.Chellappan@moffitt.org. H. Lee Moffitt Cancer Center is an Equal Opportunity/Affirmative Action Employer. http://www.newscientistjobs.com/jobs/job/research-scientist-and-postdoctoral-positions-in-the-biological-engineering-department-and-the-center-for-environmental-health-sciences-at-mit-ma-massachusetts-200638759.htmThu, 12 Nov 2009 22:24:24 +0000180785RESEARCH SCIENTIST AND POSTDOCTORAL POSITIONS IN THE BIOLOGICAL ENGINEERING DEPARTMENT AND THE CENTER FOR ENVIRONMENTAL HEALTH SCIENCES AT MIT With the recent honor of a NIH Director’s Pioneer Award, Leona Samson is now building a team of scientists and engineers with the goal of developing high-throughput multiplexed approaches to measuring DNA repair capacity for multiple types of DNA damage in human cells and tissues. Applicants must have a PhD in biology, chemistry, bioengineering, or equivalents. They must also have a strong desire to develop new technologies that will contribute to the prevention of, and treatments for, human diseases that are influenced by DNA repair and other cellular responses to DNA damage. Applications should be sent by email to Leona D. Samson Biological Engineering Department Biology Department Director, Center for Environmental Health Sciences David H. Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology lsamson@mit.edu MIT is an Equal Opportunity Employer. http://www.newscientistjobs.com/jobs/job/tenure-track-faculty-position-assistant-professor-level-cambridge-ma-whitehead-institute-for-biomedical-research-and-massachusetts-institute-of-technology-ma-massachusetts-200638749.htmThu, 12 Nov 2009 19:34:10 +0000180778TENURE TRACK FACULTY POSITION AT THE WHITEHEAD INSTITUTE AND DEPARTMENT OF BIOLOGY, MASSACHUSETTS INSTITUTE OF TECHNOLOGY The Whitehead Institute and Dept of Biology at M.I.T. are seeking an outstanding scientist for a tenure track faculty position at the Assistant Professor level. We are interested in candidates who are pursuing fundamental problems in molecular, cellular, or organismal biology, including vertebrate and invertebrate systems. Areas of interest include but are not limited to development, genetics, and disease models. A successful applicant will be expected to develop a significant, independent research program and to share our commitment to excellence in undergraduate and graduate education. Applicants should submit curriculum vitae and a summary of current and proposed research programs, and should arrange for three letters of recommendation to be sent to David C. Page, Director, by clicking Apply Now. Completed applications will begin to be considered on November 1, 2009. Whitehead/MIT is an Affirmative Action/Equal Opportunity employer. Qualified women and minority candidates are especially encouraged to apply. http://www.newscientistjobs.com/jobs/job/assistant-professor-host-pathogen-interactions-manhattan-ks-academic-ks-kansas-200635745.htmTue, 10 Nov 2009 21:49:28 +0000176267The Division of Biology at Kansas State University invites applications for a tenure-track Assistant Professor faculty position to study the interactions between animal or human viruses or eukaryotic parasites and their hosts or vectors, including studies on the evolution of such associations. The successful candidate will establish a vigorous, extramurally funded research program and contribute to graduate and undergraduate instruction. Excellent facilities exist at K-State, including a newly constructed BSL3 building located on campus. A Ph.D. or equivalent and post-doctoral training are required. More information, including application instructions, can be found by clicking Apply Now. Questions should be directed to Dr. Rollie Clem, Search Committee Chair (rclem@ksu.edu). Review of applications will begin November 30, 2009 and continue until the position is filled. KSU is an EOE. Criminal background checks are required for all employees. http://www.newscientistjobs.com/jobs/job/nih-funded-postdoctoral-position-dept-of-radiation-oncology-pa-pennsylvania-200635416.htmTue, 10 Nov 2009 15:26:59 +0000176078NIH-funded Postdoctoral position is available immediately to study the molecular mechanisms of tumor cell adaptation to hypoxic and metabolic stress and the role of the Unfolded Protein Response in tumor progression (see http://www.xrt.upenn.edu/Koumenis.shtml). Highly motivated individuals with 0-3 yrs of postdoctoral experience, a Ph.D. in cancer biology or a related area are encouraged to apply. Preference will be given to candidates with experience with molecular biology techniques and animal tumor models. Competitive salary and a generous benefits package commensurate with experience will be provided. The University of Pennsylvania is an equal opportunity, affirmative action employer. Women and minority candidates are strongly encouraged to apply. Please submit curriculum vitae, a brief statement of research interests, and contact information for three references by e-mail to: Constantinos Koumenis, Ph.D., by clicking Apply Now below. http://www.newscientistjobs.com/jobs/job/senior-in-vitro-scientist-neurosciences-dmpk-harlow-gsk-united-kingdom-200635181.htmTue, 10 Nov 2009 12:00:39 +0000175819Senior In vitro Scientist Neurosciences DMPK Harlow - Essex, South East England GlaxoSmithKline is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create a platform for the delivery of strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better and live longer. The Neurosciences Centre of Excellence for Drug Discovery (N CEDD) is engaged in the discovery of effective treatments in the areas of pain, Alzheimer’s disease, schizophrenia and other neuropsychiatric disorders. The Drug Metabolism and Pharmacokinetics (DMPK) department works closely with Biology and Medicinal Chemistry colleagues as an integral part of the drug discovery process. Job Details We are seeking a Senior In vitro DMPK Scientist to work within this multidisciplinary drug discovery environment, to supervise a team of in vitro scientists responsible for conducting a range of in vitro assays relevant to understanding the metabolism and disposition of potential drug candidates. The ideal candidate will have some or all of the following attributes: • Extensive understanding and hands-on competency in drug metabolism and enzymology and state of the art in vitro technologies. • Ability to critically evaluate recent literature, scientific data and impact of study design. • Ability to develop in vitro DMPK strategies to solve programme related issues; collation and review of in vitro structure-activity data to influence programme strategies. • Technical expertise to implement validated new enzyme / cell based in vitro DMPK assays and technologies. • Experience of assay automation and bioanalysis: - Knowledge of enzyme kinetic modelling packages (e.g. Grafit, Prism, simCYP). - Laboratory management and operational supervision of a team of in vitro DMPK scientists. • Well organised and able to maintain accurate data management of scientific records and ensure overall quality of scientific work. • Management of multiple assignments and flexibility to react positively to meet changing priorities and deadlines. • Understanding of the drug discovery process up to PoC. • Experience of establishing and managing internal and external collaborations. • Communication and matrix working skills that contribute to a positive work environment that fosters teamwork, innovation and professional development. The position provides the opportunity to work in a dynamic environment making a practical and intellectual contribution whilst engaged with the drug discovery process in the Neurosciences CEDD. Basic qualifications required: • Ph.D, or equivalent, in the field of in vitro drug metabolism and enzymology. • Laboratory management and operational supervision of a team of in vitro DMPK scientists. Preferred qualifications: Ideally you will have a Ph.D with post-doctoral experience in a drug discovery environment, specifically in drug metabolism and pharmacokinetics. This could include expertise within in vitro PK predictive scaling or transporters, with a record of implementing new technology. When applying for this role, please use the 'cover letter' of the on-line application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. Closing Date for applications: Wednesday 2nd December 2009. To Apply: At GSK we provide a supportive working environment, and a range of development challenges and opportunities. We also offer competitive benefits and compensation packages designed to attract and to retain the very best. For confidential consideration and efficient processing, please apply online via GSK’s online application system by clicking on the Apply button. Thank you for taking the time and effort to apply for this role. All data processed in accordance with the provisions of the Data Protection Act. GSK is an equal opportunities employer and is proud to promote an open culture, encouraging people to be themselves and giving their ideas a chance to flourish. To enable GSK to meet its commitment as a two ticks employer please let us know if you have a disability. http://www.newscientistjobs.com/jobs/job/postdoctoral-research-position-in-indiana-200634689.htmMon, 09 Nov 2009 20:00:28 +0000174392A POSTDOCTORAL RESEARCH POSITION is available to study cellular and molecular mechanisms of the development of pulmonary emphysema focused on the role of cellular autophagy in pulmonary emphysema and sphingolipid modulation of chronic lung injury. The applicant will join the laboratory of Irina Petrache, M.D., which is one of many highly interactive groups located in the Center for Immunobiology at the Indiana University School of Medicine – www.cimb.medicine.iu.edu. Applicants should have a strong background in cellular and molecular biology and signaling mechanisms. Experience in mammalian tissue culture and animal models is desired. U.S. citizenship or permanent residency required. The position is NIH funded. Expertise in translational studies is highly desirable. Interested applicants should send a C.V., and names of three references to: Ms. Shelley Hall, Human Resource Specialist, (please find full mailing address below by clicking View Contact Details) email by clicking Apply Now. Indiana University is an equal opportunity/affirmative action institution. Minority women are encouraged to apply. In addition, it is the University’s policy to provide reasonable accommodations for qualified persons with disabilities. http://www.newscientistjobs.com/jobs/job/assistant-or-associate-professor-tenure-track-milwaukee-wi-usa-wi-wisconsin-200634646.htmMon, 09 Nov 2009 17:59:37 +0000174368Tenure Track Faculty Position in Stem Cell Biology and Regenerative Medicine Medical College of Wisconsin Department of Cell Biology, Neurobiology and Anatomy (http://www.mcw.edu/cellbiology.htm)/Regenerative Medicine Program (http://www.mcw.edu/regenerativemedicine.htm). A tenure track faculty position at the Assistant or Associate Professor level is available for a developmental/cell biologist that uses cellular and/or molecular-genetic approaches to address fundamental aspects of cell differentiation. Candidates interested in the study of regenerative medicine using stem cells are particularly encouraged to apply. Competitive salary, laboratory space and start-up funds are available. Candidates at the Associate Professor level are expected to bring a vigorous research program with significant extramural funding. Current research strengths in the department include developmental biology of the liver, gastrointestinal, cardiovascular, and ocular systems. A Ph.D. or MD/Ph.D. degree (or equivalent), plus additional postdoctoral experience are essential. Interested individuals should send a resume, research plans, and the names of three references to: Dr. Stephen A. Duncan Chairman, Search Committee Regenerative Medicine Program Department of Cell Biology, Neurobiology and Anatomy (please find full mailing address below by clicking View Contact Details) The Medical College of Wisconsin in Milwaukee, Wisconsin is a private freestanding institution established in 1967 that enrolls approximately 800 medical students, 440 graduate students, and 200 scientists engaged in postdoctoral research. MCW is one of the fastest growing medical colleges in the U.S. and ranks in the top third of all US schools receiving NIH support. In FY 2008-09, faculty received approximately $146 million in external support for research, teaching, training and related purposes. AA/EOE