http://www.newscientistjobs.com/jobsNew Scientist Jobshttp://www.newscientistjobs.com/jobs/job/hot-job-associate-study-manager-switzerland-200644733.htmFri, 20 Nov 2009 14:15:26 +0000195232HOT JOB!!Want to take the next step in your career in Switzerland?Associate Clinical Research Specialist. My client is an innovative and enterprising global Medical technologies company who are well established and well respected within the industry. They are a successful solutions oriented company who are proud of their continued success. They are looking for a Clinical Research Specialist to join their growing team. This is a good opportunity for the right candidate to develop and gain experience within an international environment. Please contact me for more information on this role, Ludo Doche at l.doche@nonstop-pharma.com or by calling me directly on +44 (0)207 234 05 50 You will gain international experience as you will be working on several majors international studies. The successful candidate will be assisting in the design, planning and implementation of clinical studies and writing the clinical protocol, monitoring plans, preparing materials relative to the company's clinical operations, according to the regulatory standards. You will bridges the responsibilities of the Study Coordinator and the Senior Study Specialist. This is a permanent Associate Clinical Research Specialist role - so in the current economic situation it is an opportunity to be grabbed! The right candidate will bridges the responsibilities of the clinical Study coordinator and the Senior clinical Research specialist and focuses on study management activities. The ideal candidate for this role should have at least 3 year of post-university experiences both in monitoring and drafting documents relevant to clinical studies. He or she should have a good level of English as it is the corporate language. Other languages such as French will be a plus. Please contact me for more information on this role, Ludo Doche at l.doche@nonstop-pharma.com or by calling me directly on +44 (0) 207 940 21 12 http://www.newscientistjobs.com/jobs/job/drug-safety-manager-pharmacovigilance-switzerland-200644246.htmThu, 19 Nov 2009 16:02:19 +0000192796Drug Safety Manager - Pharmacovigilance My client, a leading pharmaceutical company are looking to recruit a Head of Drug Safety/Pharmacovigilance for their team in Switzerland. This is an excellent opportunity to join one of the world's leading pharmaceutical organisations. As Head of Drug Safety/Pharmacovigilance, you will be responsible for the monitoring of inspection readiness and implementation of corrective actions in relation to external inspections and internal audits, developing metrics for and monitoring quality compliance and input into process improvement initiatives. Responsibilities include; * Supporting the management of the Corrective Actions and Preventative Actions (CAPA) compilation for DS&E * Monitoring of the implementation of the CAPA * Monitoring of inspection readiness, including quality and consistency measures * Establishing and maintaining quality metrics for global processes within PVO * Maintaining updated efficient and uniform processes and procedures (SOPs) to assure that worldwide regulatory reporting requirements for marketed and development compounds are met. You will have; * Solid experience in a Clinical Safety Department & closely related areas e.g. Clinical Development, GCP QA * Management experience in direct & indirect leadership roles * Knowledge of global regulations for report of clinical safety * The ability to work in matrix cross-functional environments This is an exciting and challenging role, which opens up excellent personal and professional opportunities. If you would like to hear more, please forward your CV to Melissa Lee, specialist pharmaceutical recruiter at Stelfox Recruitment for immediate consideration. http://www.newscientistjobs.com/jobs/job/business-unit-manager-zurich-200643661.htmThu, 19 Nov 2009 11:53:26 +0000192129The right candidate will have at least five years experience in international marketing of pharmaceutical products. The main responsibilities will be to develop my client business strategy and related action plans for the unit, drive and monitor implementation of the unit strategic plan. Others tasks include: -Represent international marketing in interdisciplinary project teams and drive and monitor cross-functional realization of development action plan of the Unit franchise to ensure execution of activities that lead to the intended product innovations & approvals, pre-marketing and marketing activities -Provide strategic development and regulatory rationales leading to regulatory submissions and product/indication approvals in alignment with the unit strategy -Define, drive and monitor development of the client next generation products &D - Develop medical and marketing messages, product positioning concepts, publication plans for the unit products, as well as define the congress strategy Please contact me for more information on this role, Ludo Doche at l.doche@nonstop-pharma.com or by calling me directly on +44 (0)207 234 05 50 http://www.newscientistjobs.com/jobs/job/clinical-project-manager-switzerland-high-salary-switzerland-200643641.htmThu, 19 Nov 2009 11:50:11 +0000192114Clinical Project Manager - Switzerland - High salary Our client is a large pharmaceutical company that has been making good progress with some of their main projects in the pipeline. Due to this situation, the company is now investing in the R&D and clinical department in order to improve their research. The company is now looking for a clinical project manager, which has solid experience on an international level to join the team and work on some of the main projects the company is currently running. This is a great opportunity to gain experience in Switzerland and gain a solid financial package. The main requirements for this role are the following: * Previous experience as a clinical project manager on an international level * Good working knowledge of English * Proven clinical research experience For a confidential discussion and to find out more information about this role please contact the clinical research desk at NonStop on 0207 940 2106 or by e-mail to clinical@nonstop-pharma.com http://www.newscientistjobs.com/jobs/job/post-doctoral-position-in-enzyme-characterization-switzerland-200643034.htmThu, 19 Nov 2009 08:08:13 +0000191340Job description Are you scared of Michaelis–Menten, Lineweaver–Burk, allostery, cofactors, metabolism, pathways and so on? In this case, we are not interested in your application. But if enzymes do not scare you but rather motivate your interest, please read on! A post-doctoral position is available in the CALIPHO group (Computational Analysis and Laboratory Investigation of Proteins of Human Origin), a new research laboratory which is a joint endeavor between the Faculty of Medicine of the Geneva University and the Swiss Institute of Bioinformatics (SIB). Job tasks The research project will be part of the BattleX project funded by systemsx.ch. The goal of the whole consortium is to establish a genome-scale model of metabolic host-pathogen interactions and use it as a basis for novel strategies to combat infections. In this context, the goal of the post-doctoral project will be to discover and characterize human proteins that have been predicted, using bioinformatics analysis, to act as enzymes. The candidate will need to apply a wide panel of experimental techniques, from the fields of biochemistry, molecular biology and cell biology. Profile requirements PhD in biochemistry or enzymology. Length of contract: two years, extendable to 4 years. Start date: Earliest: February 1, 2010 (negotiable) Place of work: Geneva Please send your application to Send your CV, the names of references and a letter of motivation by email to: calipho_hr@isb-sib.ch This e-mail address is being protected from spambots. You need JavaScript enabled to view it with "MOW-3" as the message subject line before 15th December 2009. Amos Bairoch and Lydie Lane CALIPHO group leaders http://www.newscientistjobs.com/jobs/job/medical-clinical-safety-manager-zurich-200640916.htmTue, 17 Nov 2009 12:10:34 +0000187500_Responsible, in close collaboration with Clinical Operations and Clinical Development, to organize the exchange of all safety relevant information between the Drug Safety Department and involved CROs for all clinical development projects. _Responsible, in close collaboration with Clinical Operations and involved CROs, for the submission of individual safety reports (SUSARs) and reports of aggregated clinical data (Annual Safety Reports) according to legally required timelines to Health Authorities, Ethical Committees and external Safety Review Boards. _Responsible for data unblinding whenever appropriate and data reconciliation of clinical safety data entered into the safety database after finalization of a clinical development project. _Support Clinical Development/Regulatory Affairs/Affiliates on ad hoc questions concerning medical / clinical safety (expert reports, regulatory dossiers) _Ensure high quality safety relevant texts and reports _Ensuring compliance with regulatory agencies _Drug Safety Monitoring, Drug safety signal detection and implementation of risk management plans _Drug Safety related inputs into study protocols, study reports and SmPC/Patient Leaflet _Ensure correct communication and information on drug safety topics, in particular drug safety review of promotional and medical affairs material _Drug Safety Training for staff (initial and continuous) _Participation of Emergency phone team _Management of Medical and Clinical Drug Safety Officers Minimum Requirements _Medical Degree, ideally Specialist in Internal medicine, Anesthesiology or Pharmaceutical Medicine _Experience in international Drug Safety, ideally operational as well as clinical drug safety _Experience in data analysis, signal detection and benefit/risk evaluation _Excellent knowledge of international regulations (ICH, Volume 9A/10, FDA regulations), incl. experience with health authority inspections. _Fluency in English Preferred Requirements _Experience in Pharmaceutical Medicine, particularly Clinical Research, and/or experience in Clinical Pharmacology _Knowledge and experience in Pharmacoepidemiology _Demonstrated ability to set up and implement drug safety strategies, risk management plans, develop Drug Safety systems and procedures, and elevate and resolve issues. _Demonstrated proficiency in problem-solving with respect to pharmaceutical Drug Safety issues. _Good computer literacy with experience with safety data bases (Aris G preferably) _Capable of exercising oversight in communications and problem solving liaisons with internal and external customers. _Capable of exercising oversight in the maintaining understanding of Drug Safety issues with Clinical team members and ensure appropriate training through workshops, seminars, courses, literature, or other means consistent with Drug Safety development. http://www.newscientistjobs.com/jobs/job/phd-position-in-computational-evolutionary-genomics-switzerland-200638500.htmFri, 13 Nov 2009 16:18:49 +0000182456Job description We are looking for a highly motivated and innovative PhD student candidate (~4 years) to explore the wealth of genomic data from evolutionary perspective using bioinformatics approaches. Our group has a broad range of interests related to the functional evolution of genomes, and actively contributes to international genome analysis consortiums. The specific project will be developed together with the candidate. The project will be supervised by Prof. E. Zdobnov at the Department of Genetic Medicine and Development of the University of Geneva Medical School. We are also part of the renowned Swiss Institute of Bioinformatics, and offer a stimulating research environment with excellent facilities. The international city of Geneva, described as 'the smallest of the large capitals', offers a vibrant city life within easy reach of the picturesque lake and stunning Alps. Closing date for applications: 15 November 2009. Profile requirements The ideal candidate should have a strong background in bioinformatics, including programming skills (or the willingness and drive to acquire them), and a good understanding of molecular biology (preferably with some experience/background in molecular evolution). A Diploma or MSc degree in Biology or Bioinformatics, practical experience in the Unix environment, and fluency in English are required. Please send your CV, statement of research interest, and names and contact details of at least two referees by e-mail to Evgeny.Zdobnov@isb-sib.ch http://www.newscientistjobs.com/jobs/job/molecular-oncology-data-analyst-at-swiss-institute-of-bioinformatics-lausanne-200638494.htmFri, 13 Nov 2009 16:18:43 +0000182452Job description We are undertaking a project to characterize and biologically understand molecular heterogeneity of a specific cancer types by combining studies with multiple types of genomics and epigenomics technologies, as well as combining public and proprietary data To complete the data analysis team we seek a versatile highly motivated and well-trained postdoctoral researcher with an interest in biomolecular data mining with high throughput data. In particular, the scientist will explore connections between the different molecular profiles (mRNA and miRNA expression, DNA methylation, gene mutation and CNV) and interpret the data in the contest of biochemical signaling pathways and their relevance to tumor growth and progression. Job tasks -Integration of molecular profile data with prior biological knowledge (biological function and pathway databases, role in diseases) -Biological interpretation to make sense out of results from data analyses of large bodies of complex data -Interrogate data with plots, data mining techniques and statistical analysis in collaboration with statisticians and molecular biologists to find patterns, generate hypothesis and propose ways to validate them -Secondary responsibilities: Contribute to bioinformatics data analysis -participate in meetings -write documentation and reports Profile requirements -PhD in biochemistry, bioinformatics or equivalent -excellent knowledge of cancer biology and biochemistry -enthusiastic interest for research at the crossroads of experimental and computation methods and of basis and clinical research -excellent interpersonal skills for working within a team of biologists and programmers. -high-level understanding of bioinformatics and statistics methods -good English speaking and writing skills Preferences -Preference will be given to candidates who have excellent written and oral communication skills, an in depth understanding of the biological questions, and are good team players. -experience with genomic databases and with software tools for exploration of biochemical pathway activity (Partek, Ingenuity/MetaCore, Genome Studio or the like) -experience in the analysis of high-throughput genomic / genetic data, particularly the interpretation of molecular profile or genotype data -knowledge of biological pathways-regulation principles and mechanisms -sound background in Computer Science, Engineering, Mathematics, Physics, Bioinformatics or related quantitative science. Salary & Benefits Salary: 75 - 100 kCHF (50 - 70 k€) per year, depending on experience and qualifications. SIB offers an attractive social security system. Additional information SIB is a not-for-profit organization that offers excellent bioinformatics infrastructure and a stimulating research environment. In addition to powerful computer hardware, the SIB branches maintain a large collection of molecular biology databases and software packages. The scientist will be working in a multidisciplinary team with great expertise in applications of bioinformatics and biostatistics to translational research. The project is in collaboration with the biomarker discovery unit of a major pharmaceutical company. The position will open opportunities for careers in basic or applied research in academia or in the private sector. Please send your application to The application should include a cover letter, with summary of motivation, research interests and past accomplishments; curriculum vitae including description of skills and experiences; names and email addresses of at least three referees. Please also indicate if you are already authorized to work in Switzerland or the EU (visa). Applications will be considered as soon as possible. They and should be sent with Subject line: “Application Biomarkers BCF-October2009” to: Job contact person Dr. Mauro Delorenzi Head BCF Swiss Institute of Bioinformatics (SIB) Quartier Sorge - Batiment Genopode CH-1015 Lausanne Mauro.delorenzi@isb-sib.ch http://bcf.isb-sib.ch Lausanne [www.lausanne.ch/] is a beautiful lakeside city in Switzerland, in a French speaking area close to the Alps. http://www.newscientistjobs.com/jobs/job/laboratory-technician-within-sample-submission-center-research-80-switzerland-200636268.htmWed, 11 Nov 2009 11:41:48 +0000177490Who we are At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other’s differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves. The headquarters in Basel is one of Roche’s largest sites. It is home to the Corporate Executive Committee, the Pharmaceuticals and Diagnostics Divisions and the global business functions. Roche Basel also covers the entire business chain from research, development and production through to marketing. Over 8,000 people from more than 60 countries work at the site. The Position The Sample Submission Center Basel (SSC) is a service and support unit for drug discovery in Basel. Novel chemical compounds from LI/LO activities in Research Chemistry are registered, dissolved, reformatted and distributed to various laboratories in Research Biology and Non-Clinical Safety in a short turnaround time. Several hundred individual samples are processed routinely on a daily basis using state-of-the-art laboratory equipment including fully automated storage units and liquid handlers. Precisely defined workflows ensure in time delivery of samples to screening laboratories. The position will focus on the execution of scheduled workflows. You will ensure that regular inventory procedures are completed in a timely manner according to SOP. You will be a contact person for researchers and you support non-standard requests on an as-needed basis. Your responsibility also extends into other Roche Compound Depository tasks within the group.This position is available on a part-time basis (80%). Who you are You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies, and where a job title is not considered the final definition of who you are, but the starting point. You have good organizational skills and as a team player, you feel comfortable working in a small team as well as in interacting with customers and peers on a daily basis. You have a good understanding of logistics and workflows and can work accurately according to SOPs. Experience in working with computer controlled laboratory equipment is a plus. Knowledge in handling datasets in MS Access and MS Excel would be advantageous. The position requires flexibility as well as good communication skills in German and English, both spoken and in writing. The next step is yours. To apply today, click on the "Apply online" button below. http://www.newscientistjobs.com/jobs/job/postdoctoral-research-project-concerted-bioinformatics-approach-to-uncover-the-function-of-human-proteins-lausanne-200634931.htmTue, 10 Nov 2009 09:38:14 +0000175487About 5'000 of the estimated 20'000 human proteins are lacking experimental evidence for their function. This is clearly a major issue in any systems biology approach, as it seriously impairs the modeling of biological processes. The goal of this research project is to evaluate the potential of data mining approaches to discover clues about the possible function of yet uncharacterized human proteins. By making the best use both of available knowledge resources and repositories and the predictive power of state-of-the-art bioinformatics tools, our ambition is to supply suggestions for possible wet-lab experiments which would be carried out to reveal the function of the targeted proteins. SystemX.ch, the Swiss initiative in Systems Biology is supporting this interdisciplinary pilot project (IPP) because it explores a new research direction which, while being 'high-risk', is critical to Systems Biology. The successful applicant will be working in a multidisciplinary team which has great strength in the application of bioinformatics and biostatistics to biological and medical research and which has created world known resources such as Swiss-Prot, PROSITE and the ExPASy web site. Profile requirements - PhD in computational biology, bioinformatics or computer science; - Strong background in statistics and/or machine learning techniques; - Experience in the development of new numerical methods; - Good understanding and enthusiastic interest for biology Additional information SIB is a not-for-profit organization that offers an excellent bioinformatics infrastructure and a stimulating research environment. The project is a collaboration between two SIB groups: CALIPHO, a new group headed by Amos Bairoch -who created and developed Swiss-Prot from 1986 to 2009 -and by Lydie Lane. CALIPHO is an interdisciplinary team composed of biocurators, bioinformaticians and experimentalists, whose aim is to use a variety of methodologies to help uncover the function of uncharacterized human proteins and Vital-IT, headed by Ioannis Xenarios which provides a high-performance computing environment to support the research work of its partners in areas ranging from sequence analysis through molecular modeling to image processing. Duration: One year possibly renewable with new fundings. http://www.newscientistjobs.com/jobs/job/data-manager-neuchatel-200631970.htmThu, 05 Nov 2009 12:12:06 +0000180044THE COMPANY Philip Morris International (PMI) is the leading international tobacco company, with seven of the world's top 15 brands, including the world's number one brand. PMI has more than 75,000 employees and its products are sold in approximately 160 countries. The Company held an estimated 15.6% share of the international cigarette market outside of the United States in 2008. PMI is an Equal Opportunity Employer. For more information, please click the link within the 'View Contact Details' section below. The primary mission of the PMI Research & Development Centre is to research and develop new products which may have the potential to reduce the risks of tobacco related diseases. Furthermore, the PMI R&D team is is working to discover alternative uses for the tobacco plant. To strengthen the department of Tobacco Platform Development in Neuchâtel, Switzerland, we are looking for a: Data Manager THE POSITION The Data Manager will increase the implementation speed, the quality and the value of the Tobacco Molecular Farming platform by combining technical expertise and service orientation through the design and management of a data management system. Main accountabilities: • Maximize the appropriate use of information technology, data modeling and analysis techniques to support the implementation of the Tobacco Molecular Farming (TMF) platform • Develop Quality by Design actionable plan to implement and maintain data management tools and capabilities • Liaise between Computational Science & Bioinformatics and Tobacco Technology for development and maintenance of LIMS and ELN applications • Manage the execution of the plans for the implementation of the TMF data management system • Ensure the completeness, accuracy, consistency and traceability of all data so that they meet the quality standards in line with regulatory requirements • Monitor and report progress of data management, integration and analysis • Ensure systematic application of six sigma principles for data driven process development • Interpret, evaluate, and interrelate research data derived from TMF to guide research efforts in TAT aimed at identifying best material, practices and processes for successful molecular farming • Act as technical leader to Senior Management THE PERSON Education: • PhD in Life Sciences, Chemistry or Physics with post-doctoral and work experience Work experience: • Proven relevant work experience in the field of life sciences information management, more specifically informatics, data analysis and management • Track record of several years of cutting edge research in this field as well as data analysis, information and knowledge management Additional skills and knowledge: • Expert and extensive knowledge of advanced principles, theories and concepts in the field of information and knowledge management, design of experiment and data analysis • Key strengths: scientific creativity and passion for discovery, anticipation, risk taking, sense of purpose and people management • Fluent English We offer an excellent salary and benefits package as well as relocation allowance (where appropriate). If you match our profile and you are interested in joining our dynamic team of professionals, please reply to our on-line recruitment site by clicking the Apply Now button below. http://www.newscientistjobs.com/jobs/job/postdoctoral-positions-for-interdisciplinary-research-to-uncover-mechanisms-of-cyclic-di-gmp-signaling-switzerland-academic-basel-200631592.htmThu, 05 Nov 2009 10:02:49 +0000168226The SIB Swiss Institute of Bioinformatics, is an academic non-profit foundation whose mission is to provide core bioinformatics ressources to the national and internationa life science community and to coordinate the field of bioinformatics in Switzerland. Four postdoctoral positions are available at the SIB Swiss Institute of Bioinformatics and at Biozentrum of the University of Basel within an interdisciplinary Sinergia project funded by the SNF, which aims at understanding the molecular basis underlying the cellular c-di-GMP signaling network in bacteria (for a recent review see: Schirmer and Jenal, Nature Reviews Microbiology 7(2009)724 ). Structural, dynamic, and functional aspects of c-di-GMP signaling components are investigated embedded within an interactive environment of research teams in computational,structural, and cellular biology. Techniques include bioinformatics analysis, crystal structure determination and homology modeling of representatives of the most important signaling components. The conformational dynamics of these components in solution will be addressed by single molecule FRET experiments to understand their function and regulation. Mechanistic models of catalysis and regulation will be validated and refined systematically using in vitro and in vivo assays as readouts using well-developed pathogenic and non-pathogenic model system for c-di-GMP signaling." We seek highly motivated and well-trained individuals with a specific interest in interdisciplinary research and close scientific interactions. We offer full, long-term SNF-funded positions with competitive salaries and a highly dynamic and well-equipped research environment at the Biozentrum. Position in molecular biology, microbiology, or biochemistry (group Urs Jenal) Candidates should have a strong background in protein biochemistry and/or molecular biology techniques. Position in structural biology or biochemistry (group Tilman Schirmer) Experience in crystallography and/or enzymology advantageous, but not mandatory. Position in biophysics, biochemistry, or molecular biology (group Dagmar Klostermeier) Candidates should have a strong background in optical spectroscopy, preferentially at the single molecule level, and/or molecular biology and protein biochemistry techniques. Position in bioinformatics or computational biology (group Torsten Schwede) Candidates should have a strong background in bioinformatics, protein sequence analysis, data mining and/or computational structural biology. Positions are available immediately. Please submit your application letter including curriculum vitae, a brief description of previous research experience, and contact information of two references (preferably by email). For further information you may also contact the group leaders. http://www.biozentrum.unibas.ch/jenal/ http://www.biozentrum.unibas.ch/schirmer/ http://www.biozentrum.unibas.ch/klostermeier/ http://www.biozentrum.unibas.ch/schwede/ http://www.newscientistjobs.com/jobs/job/clinical-data-managers-geneva-switzerland-200631538.htmThu, 05 Nov 2009 09:36:11 +0000168148Clinical Data Managers - Geneva Central Laboratory Services, Geneva Covance is one of the world's largest and most comprehensive drug development services companies with revenues in excess of $1.5 billion, global operations in over 22 countries, and over 9,500 employees working from 33 offices. Covance provides innovative and practical solutions to the challenge of drug development, enabling biotechnology, pharmaceutical and agrochemical companies to get their products to market sooner. With extensive experience and expertise in every stage of drug development, Covance is a recognised industry leader. At Covance, we help make the miracles of medicine reality. Helping our clients turn discoveries into marketed products, we are a catalyst that enables medicines to change and save lives. Covance Central Laboratory Services, our European laboratory based in Geneva, is the leading central laboratory in Europe, dedicated to clinical laboratory testing. We offer opportunities to work on diverse, challenging projects with bright, interesting colleagues while building a flexible and rewarding career. So if you like the challenge of working in a fast-paced, results-driven organization, Covance is the place for you. Interacting with clients' Data Management departments, you'll translate and transfer the Covance database into an electronic clinical file using a customized format that meets the needs and expectations of the customer. If you want to start a rewarding career within a diverse global culture, why don't you take a look at all our opportunities at our website http://www.newscientistjobs.com/jobs/job/project-managers-geneva-switzerland-200631537.htmThu, 05 Nov 2009 09:36:08 +0000168147Project Managers - Geneva Central Laboratory Services, Geneva Covance is one of the world's largest and most comprehensive drug development services companies with revenues in excess of $1.5 billion, global operations in over 22 countries, and over 9,500 employees working from 33 offices. Covance provides innovative and practical solutions to the challenge of drug development, enabling biotechnology, pharmaceutical and agrochemical companies to get their products to market sooner. With extensive experience and expertise in every stage of drug development, Covance is a recognised industry leader. At Covance, we help make the miracles of medicine reality. Helping our clients turn discoveries into marketed products, we are a catalyst that enables medicines to change and save lives. Covance Central Laboratory Services, our European laboratory based in Geneva, is the leading central laboratory in Europe, dedicated to clinical laboratory testing. We offer opportunities to work on diverse, challenging projects with bright, interesting colleagues while building a flexible and rewarding career. So if you like the challenge of working in a fast-paced, results-driven organization, Covance is the place for you. You'll interact with clients and internal departments to develop customized protocol specifications, taking full accountability for the deliverables, monitoring running studies according to the needs of the customer. If you want to start a rewarding career within a diverse global culture, why don't you take a look at all our opportunities at our website http://www.newscientistjobs.com/jobs/job/scientific-programmer-for-web-development-in-computational-structural-biology-switzerland-academic-basel-200629145.htmWed, 04 Nov 2009 00:00:00 +0000165205The SIB Swiss Institute of Bioinformatics, is an academic non-profit foundation whose mission is to provide core bioinformatics resources to the national and international life science research community and to coordinate the field of bioinformatics in Switzerland. We are looking for a highly motivated scientific programmer to join our project team working in the field of automated protein structure prediction servers and protein structure model databases. We are collaborating with the leading institutions of the PSI Protein Structure Initiative in developing the Protein Model Portal of the Nature - PSI Structural Genomics Knowledgebase. We are seeking a highly motivated scientific programmer who will take responsibility for web site development as part of our programming team. Requirements We are looking for a highly motivated scientific programmer with background in computational sciences, software engineering, computational biology, or related fields with appropriate knowledge and experience. Excellent programming skills (PERL, Python, Java) and experience in practical applications of web technologies (php, AJAX, cgi, JavaScript), databases (MySQL), web services, and web servers (Apache) in a Linux/Unix environment are essential. Successful candidates have strong communication skills and enjoy working in a dynamic development team. Practical working experience in an academic environment would be beneficial. Finally, applicants must have a strong desire to learn the specific requirements and algorithmic principles of applications in the field of bioinformatics and computational structural biology. Our Offer You will be working in a highly stimulating and international research environment as part of the Research core program “Computational and Systems Biology” at the Biozentrum, University of Basel and the Swiss Institute of Bioinformatics. The salary offered is according to the guidelines of the Swiss Institute of Bioinformatics. The position is available immediately, starting date upon agreement. If your profile and qualifications meet these requirements, please send us your CV with a cover letter, only by clicking the Apply Now button below. Every candidacy will be treated with total confidentiality. http://www.isb-sib.ch http://www.biozentrum.unibas.ch http://www.newscientistjobs.com/jobs/job/postdoctoral-positions-in-both-experimental-and-computational-biology-basel-200628916.htmTue, 03 Nov 2009 11:12:44 +0000164680We offer several postdoctoral positions in both experimental and computational biology for an integrated effort that aims to decipher the transcriptional regulatory circuitry of cellular differentiation. Our joint project aims to identify general principles through which chromatin state, epigenetic modifications, and transcription factors cooperate to achieve cellular differentiation in mammals. Using functional genomics approaches we will obtain quantitative time courses of transcription and epigenetic states genome-wide in well-defined mouse differentiation systems. Data will be analyzed in close collaborations between computational and experimental groups. Predictive models will be tested by targeted genetics and genomics experiments. Participating laboratories include: Gerhard Christofori, Georg Holländer, Anton Rolink, Erik van Nimwegen and Mihaela Zavolan; University of Basel Patrick Matthias, Antoine Peters, Dirk Schübeler and Susan Gasser; Friedrich Miescher Institute for Biomedical Research Successful applicants will work in a highly stimulating research environment, and will be offered training in theoretical and practical techniques. All member laboratories lie in close proximity within Basel, Switzerland, a city boasting academic and cultural excellence, located in the heart of Europe. Funding is ensured through a four-year SystemsX.ch grant. For further information visit our website by clicking the link within the 'View Contact Details' section below. Interested applicants should send their CV, a brief statement of motivation and three letters of reference by clicking the Apply Now button. Review of applications will start Dec 15, 2009. http://www.newscientistjobs.com/jobs/job/communications-manager-switzerland-200624694.htmThu, 29 Oct 2009 12:18:19 +0000163146Our Client, the SIB Swiss Institute of Bioinformatics, is an academic non-profit foundation whose mission is to provide core bioinformatics resources to the national and international life science research community and to coordinate the field of bioinformatics in Switzerland. To develop and reinforce its corporate image as well as its internal and external communications, the SIB is looking for a: COMMUNICATIONS MANAGER This position, located in Lausanne, will report directly to the SIB Executive Director. Its principle role will be the organization, planning and implementation of the internal and external communication of the SIB, as well as the further development of the communication strategy. The main responsibilities are: • Lead and coordinate global communication concept and strategy • Participate in the diffusion of the SIB company culture • Write/translate internal and external documentation • Ensure coordination of communication activities within the SIB • Release information to the media, related political departments and partner Institutions • Develop and formalize contacts with Swiss and foreign journalists • Establish and maintain press files • Coordinate information flow among SIB groups, SIB partners and SIB management • Define and supervise SIB institutional website(s) • Organize punctual events The position requires: • University degree in communication • Knowledge or at least strong interest in the scientific environment • Proven experience in similar position • Proven experience in writing scientific articles aimed at a general public, an asset • Previous experience working with the media • Perfect spoken and written English, fluent French (German an asset) • Swiss nationality or valid work permit If your profile and qualifications meet these requirements, please send us your CV with a cover letter, only by clicking the Apply Now button below. Every candidacy will be treated with total confidentiality. http://www.newscientistjobs.com/jobs/job/lab-technician-switzerland-basel-200624051.htmThu, 29 Oct 2009 09:02:32 +0000171395We are currently looking for a Lab Technician for an International Pharmaceutical company based in Basel, Switzerland. We need an enthusiastic and flexible person to Plan conduct, analyse and document pharmacokinetic studies in laboratory animals with radioactive and non-radioactive compounds. Main Duties- *Work in a small team applying state of the art technologies in different animal models *Perform in vitro studies on blood distribution and protein binding *Will handle radioactive compounds and will determine radioactivity in several matrices In return my client offers a highly competitive remuneration and benefits including - * Excellent holiday allowance * Health care * Excellent opportunities for progression So if you have commercial experience within animal handling and knowledge of Animal anatomy - please forward your CV to jody@stelfoxuk.com or call me on 01273 727930 for a more in depth discussion. http://www.newscientistjobs.com/jobs/job/lab-head-switzerland-basel-200623936.htmWed, 28 Oct 2009 17:49:45 +0000171401We are currently looking for a Research Investigator / Laboratory Head for an International Pharmaceutical company based in Basel, Switzerland. We need an passionate and flexible person to be part of a multidisciplinary and multinational team involved in the discovery of immunomodulators for the treatment of autoimmune disorders. Main Duties- *To lead a laboratory contributing to drug discovery including target identification and validation *The lab will be in the area of in vitro immunology with emphasis on biochemical technologies *Will collaborate with other disease areas as well as R&D departments In return my client offers a highly competitive remuneration and benefits including - * Excellent holiday allowance * Health care * Excellent opportunities for progression So if you have experience within Research and human autoimmune diseases and all the pathology - please forward your CV to jody@stelfoxuk.com or call me on 01273 727930 for a more in depth discussion. http://www.newscientistjobs.com/jobs/job/lab-head-immunology-basel-switzerland-basel-200623932.htmWed, 28 Oct 2009 17:47:02 +0000171396We are currently looking for a Lab Head in Immunology for an International Pharmaceutical company based in Basel, Switzerland. We need a passionate and flexible individual to lead the development and management of the immune system and infectious models lab. Main Duties- *Manage and supervise scientific, technical and admin duties within your area *Develop, implement, validate and maintain state of the art technologies and systems *Perform target reviews and translational immune system safety assessments for early and late development projects *Develop in vitro and in vivo methods for drug induced immunotoxicology studies In return my client offers a highly competitive remuneration and benefits including - * Excellent holiday allowance * Health care * Excellent opportunities for progression So if you have commercial experience within Immunology/Immune system and also strong knowledge of cell biology and biochemistry - please forward your CV to jody@stelfoxuk.com or call me on 01273 727930 for a more in depth discussion.