Add

Sr Res Sci –Carbohydrate & Conjugates, Vaccine Research Early Development

As a member of Vaccine Research East– Early Development group, the qualified candidate will develop and qualify analytical methods (in line with ICH guidelines for the characterization and release of biopolymers (polysaccharides, proteins, glycoconjugates and their intermediates) as drug substance or in formulated drug product, and transfers to support early stage of vaccine development. The candidate will work across multiple analytical functions and cross functional project teams. The candidate will also serve as technical counsel to senior leadership and is expected to train and mentor other scientists.

- The qualified candidate is expected to develop assays required for the testing of biopolymers (polysaccharides, proteins, glycoconjugates and their intermediates) as drug substance or in formulated drug product, perform assay qualifications and transfer to support early stage of Vaccine Development.
- The candidate is expected to design and execute analytical method development and qualification strategies for Vaccine samples with a high degree of independence.
- The candidate is expected to design and perform in process assays to support process development for polysaccharide expression, purification, monitoring conjugation processes and glycoconjugate purification.
- The candidate is expected to design and develop analytical assays for testing the stability of biopolymers (polysaccharides, proteins and glycoconjugates).
- The candidate should have considerable knowledge and experience in the development and qualification of analytical assays for polysaccharides, proteins and conjugates’ using LC-MS, GC MS, MS, NMR, HPLC, MALS/AFFF and HPAEC PAD. The candidate must have a solid understanding in HPLC theory and applications as applied to analytical method development. Familiarization with common modes of HPLC separation such as, RP-HPLC, IEX-HPLC, SEC, and column chemistry for protein separation is also required.
- The candidate is expected to author SOPs, reports, technical documents, generate appropriate documentation for transfer of the methods,
- As required, the candidate is expected to contribute portions of patents, regulatory documents or manuscripts.
- The candidate will also train staff in specific technologies and supervise their work as needed.
- The candidate is expected to maintain a safe and productive work environment, keep an accurate and reliable laboratory notebooks and maintain broad overview of relevant scientific literature

Qualifications:
- Ph.D. in Organic Chemistry, Analytical Chemistry or related field + 2-years experience.
- Industrial experience in assay development is desirable.
- The candidate should have expertise in characterization of complex carbohydrates and glycoconjugates.
- Extensive experience in the development of novel protocols and methods using the following technologies, LC-MS, GC-MS and HPLC.
- Publications are a must.
- Experience in training analytical scientists in a team environment.
- Experience with ICH guidelines is desirable.

Behavioral Competencies:
- Good communication/presentation and writing skills are required.

Benefits:
At Pfizer, we've long recognized that our colleagues are our most important asset. We value our colleagues, recognize their talent, encourage their growth and reward their performance. It's a terrific environment that enables people to contribute, to do their best, and to achieve their potential.

Throughout our history, a legacy of caring for others has been at the heart of everything we do at Pfizer. This commitment is no less important when it comes to our employees.

When you choose a Pfizer career, we provide the resources to help you develop and succeed both in your career and your personal life. One way we can achieve this is through our comprehensive benefits program, which offers employees and their eligible dependents the variety and flexibility to help address their needs at different stages in life.

Company Profile:
At Pfizer, we apply science and our global resources to improve health and well-being at every stage of life. We strive to set the standard for quality, safety and value in the discovery, development and manufacturing of medicines for people and animals.

Today, Pfizer Inc. is an even more diversified health care company because of its acquisition of Wyeth. The combined company has a robust and growing pipeline with product offerings in human, animal, and consumer health, including vaccines, biologics, small molecules and nutrition. It has medicines in numerous growing therapeutic areas, premier scientific and manufacturing capabilities and a leading global presence.

Pfizer has medicines in numerous growing therapeutic areas including Alzheimer’s disease, oncology, pain, neuroscience, diabetes and inflammation. The combination of top scientists from both companies, as well as leading scientific and manufacturing capabilities, and a global network of proof-of-concept clinical development centers, has greatly enhanced the company’s ability to innovate.

Colleagues from around the world are drawn to Pfizer because of the challenging and often groundbreaking work we do, our emphasis on innovation, and our industry leadership. They stay at Pfizer because of our commitment to their growth and development, the respect we show them as individuals, our emphasis on creativity, diversity and inclusion and our corporate values.

Learning. Growing. Succeeding. This is what a Pfizer career is made of. If you’re committed to making a difference worldwide, we invite you to apply for an opportunity with us.


HOW TO APPLY:
Please copy and paste the following URL into your browser address bar:
http://posttrak.arbita.net/cgi-bin/PostTrak.cgi?RefCode=R5926420308645