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Group Head, Biochemical & Organ Toxicology (Cambridge)

We are seeking an experienced scientist and manager to lead a Biochemical & Organ Toxicology group within Investigative Toxicology (Preclinical Safety, Exploratory Development) based in Cambridge, MA. Investigative Toxicology is using non-clinical innovative investigations to discover the mechanisms of target organ toxicity and to prevent and solve pre-clinical and clinical drug safety issues. The candidate will be responsible for the design and set-up of new experimental facilities for 3 laboratories, and the management of staff therein. The candidate will also be responsible for subsequent development, implementation and management of experimental studies. The primary deliverable of these laboratories (Endocrine & Repro-toxicology, Protein & Mitochondrial Toxicology and Biochemical & Cellular Toxicology) will be to facilitate the early identification and characterisation of toxicities during preclinical phases of drug development with a particular focus on Novartis Institute for Biomedical Research (NIBR) disease areas, expertise and technologies in Cambridge. In addition, the candidate will also work closely with Preclinical Safety Project Team Representatives to help assess potential safety liabilities associated with novel drugs and their target(s). The candidate will report to the Global Head of Biochemical and Organ Toxicology and will interact closely with colleagues in other groups as a member of cross-functional and multi-disciplinary teams (including global Investigative Toxicology & Preclinical Safety departments, NIBR and external collaborators).

Minimum Requirements
. Ph.D. degree in Biochemistry, Physiology, Cell Biology, Toxicology or a related Biological Science.
. At least 5 years of prior experience of toxicology in pharmaceutical drug development is required
. A strong expertise in endocrine toxicology and reproductive toxicology.
. Experience of managing highly skilled technical staff, laboratory equipment, consumables and safety is desirable.
. Fluency in English (written and spoken) is a must.
. Flexibility and ability to work in a team, comfortable with multitasking, excellent written and oral communication skills, independent and accurate working style, ability to plan and organise effectively, willingness to take on additional responsibilities are expected. Minimum requirements We are seeking an experienced scientist and manager to lead a Biochemical & Organ Toxicology group within Investigative Toxicology (Preclinical Safety, Translational Sciences) based in Cambridge, MA. Investigative Toxicology is using non-clinical innovative investigations to discover the mechanisms of target organ toxicity and to prevent and solve pre-clinical and clinical drug safety issues. The candidate will be responsible for the design and set-up of new experimental facilities for 3 laboratories, and the management of staff therein. The candidate will also be responsible for subsequent development, implementation and management of experimental studies. The primary deliverable of these laboratories (Endocrine & Repro-toxicology, Protein & Mitochondrial Toxicology and Biochemical & Cellular Toxicology) will be to facilitate the early identification and characterisation of toxicities during preclinical phases of drug development with a particular focus on Novartis Institute for Biomedical Research (NIBR) disease areas, expertise and technologies in Cambridge. In addition, the candidate will also work closely with Preclinical Safety Project Team Representatives to help assess potential safety liabilities associated with novel drugs and their target(s). The candidate will report to the Global Head of Biochemical and Organ Toxicology and will interact closely with colleagues in other groups as a member of cross-functional and multi-disciplinary teams (including global Investigative Toxicology & Preclinical Safety departments, NIBR and external collaborators).