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Faculty Position, Genome Stability Group

The University of Pittsburgh Cancer Institute (UPCI) and University of Pittsburgh has a strong program in Genome Stability and DNA Repair and seeks to recruit faculty at the junior and mid-career stage to develop outstanding research programs that bring approaches complementing our existing strengths. The current group consists of Chris Bakkenist, PhD (ATM signaling; DNA double-strand break repair); Laura Niedernhofer, PhD, MD (ERCC1; cross-link repair; mouse model of aging and cancer); Patty Opresko, PhD (DNA helicases; telomeric DNA damage, repair and replication); Vesna Rapic-Otrin, PhD (damage recognition by DDB; DDB-CUL4 E3 ligase and histone ubiquitination in chromatin); Robert Sobol, PhD (base excision repair; PARP & NAD+ signaling and metabolism; chemotherapeutic approaches in brain cancer); Ben Van Houten, PhD (structure-function of repair proteins; mitochondrial physiology); Yong Wan, PhD (ubiquitin-dependent proteolysis; cell cycle control; DNA damage responses). UPCI and University of Pittsburgh have world-class shared facilities including the Center for Biological Imaging (Simon Watkins, PhD) and the University of Pittsburgh Drug Discovery Institute (John Lazo, PhD). There are opportunities for extensive collaborations within the University of Pittsburgh Medical Center and Carnegie Mellon University, as well as opportunities for participation in related graduate programs.
Interested applicants working on problems in all aspects of genome stability, including, polymerase fidelity, DNA double-strand break repair, structure-function studies of DNA repair enzymes and DNA damage responses, are encouraged to apply. We seek exceptional candidates using state-of-the-art biochemical and molecular biology tools working in an array of biological systems. We are also interested in candidates combining high throughput screens with bioinformatic approaches for the analysis of large data sets. Candidates with a track record of independent funding and publications in high impact journals will be given the highest consideration.
Successful candidates will be expected to run a vibrant collaborative program supported by external funding. A competitive salary and research start-up package will be provided. The University of Pittsburgh School of Medicine is consistently among the top ten in NIH-funded medical schools in the U.S. and is located in one of America’s most livable cities.
Positions will be coordinated with Departments in the University of Pittsburgh and are tenure track. To apply, please send your curriculum vitae, a one-page summary of your research plans, and three letters of recommendation to: Bennett Van Houten, PhD, UPCI Research Pavilion, Hillman Cancer Center Suite 2.6, 5117 Centre Avenue, Pittsburgh, PA 15213-1863, email: vanhoutenb@upmc.edu. Applications will be reviewed and evaluated on an ongoing basis.
The University of Pittsburgh is an Affirmative Action, Equal Opportunity Employer.
Faculty Position
Genome Stability Group
University of Pittsburgh Cancer Institute