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Associate Research Scientist

Salary Grade: Associate Research Scientist
Salary Range: Commensurate with experience
Group Leader: Aris Floratos

The Herbert Irving Comprehensive Cancer Center is seeking an Associate Research Scientist for its Biomedical Informatics Core. The core supports the computational biology and bioinformatics needs of investigators throughout the Cancer Center on a wide range of projects in the areas of Cancer Research, including the analysis of gene expression, polymorphism, sequence, microRNA, and epigenomics data. The Associate Research Scientist will function as a bridge between Cancer Center investigators and Investigators in the Center for Computational Biology and Bioinformatics (C2B2) and the Columbia Center for the Multiscale Analysis of Genetic Networks (MAGNet). The successful candidate will be able to work and thrive at the interface between laboratory science and computational biology. This position requires a PhD in a domain related to cancer research and bioinformatics. Applicants should have a good working knowledge of a variety of platforms for genomic data analysis and, in particular, of microarray expression profile data analysis tools. The ideal candidate will be able to complement this experience with programming skills to extend existing tools and develop new tools as required by the task.

The candidate will be expected to work with scientists to understand project requirements and to provide advice and guidance on bioinformatics solutions. As a result, he or she must possess excellent interpersonal and communication skills. The candidate may also work with programming staff in designing and implementing larger scale solutions for specific projects. Projects may involve microarray gene expression data, gene sequence annotation and analysis, pathogen identification through use of Mass Spectrometry, and storage of data into databases and retrieval to web interfaces or other applications. Specific tasks might include microarray data analysis, integration of genotypic and expression data, and integration of sequence information with microarray profiles.

Minimum Qualifications:
Requires a Ph.D degree in a field related to Cancer research and the demonstrated ability to use advanced computational tools.

Additional Position-Specific Minimum Qualifications
The candidate should have working knowledge of Java, Perl and/or C++, with demonstrated experience in problem solving and programming for bioinformatics projects. Excellent organizational and communication skills are a must.

Preferred Qualifications
Experience in one or more of biological sequence analysis, molecular phylogeny, protein folding/structure or microarray gene expression analysis is desirable. Experience working with a relational database system such as MySQL would be very helpful, as would some proficiency in the PHP programming language.